Trend analysis of cardiovascular disease mortality, incidence, and mortality-to-incidence ratio: results from global burden of disease study 2017.

Trend analysis of cardiovascular disease mortality, incidence, and mortality-to-incidence ratio: results from global burden of disease study 2017.
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DOI:
10.1186/s12889-021-10429-0
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发表时间:
2021-02-25
期刊:
影响因子:
4.5
通讯作者:
Salehi M
Salehi M
中科院分区:
医学2区
文献类型:
--
作者:
Amini M;Zayeri F;Salehi M

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心血管疾病是引起全球关注的主要原因之一,因为死亡率和残疾的发病率和后果不断上升,并带来沉重的经济负担。本研究的目的是分析28 年来全球心血管疾病发病率、死亡率和死亡率/发病率(MIR)的趋势。年龄标准化的心血管疾病死亡率和发病率是从2017年全球疾病负担(GBD)研究中检索出来的,包括性别和不同的世界超级地区,在1990-2017年间每年都有数据。此外,人类发展指数来自联合国开发计划署(开发计划署)所有国家的数据库,时间间隔相同。采用边际建模方法评估了195个国家的心血管疾病发病率、死亡率和MIR的平均趋势,并分别对发展中国家和发达国家进行了评估,并澄清了这些指数与人类发展指数(HDI)之间的关系。得到的估计值表明,全球心血管疾病发病率的平均趋势在1996年之前呈上升趋势,此后呈下降趋势。从1990年到2017年,几乎所有国家的死亡率都出现了显著下降的趋势。同样,全球平均MIR速率有一个显著的微不足道的下降趋势,在这一时间间隔内的斜率为0.004。因此,在1990年至2017年期间,发达国家发病率和死亡率的下降速度明显快于发展中国家(p < 0.05)。然而,与发达国家相比,发展中国家的和平率下降幅度较小。总的来说,这项研究的结果显示,心血管疾病的发病率和死亡率总体上呈下降趋势,而心血管疾病患者的存活率则相当稳定。这些结果发出了一个令人满意的信息,即全球控制心血管疾病负担的努力相当成功。尽管如此,在发病率或死亡率有上升趋势的一些地区,迫切需要做出更多努力来提高患者的存活率,减轻这种疾病的负担。
Cardiovascular diseases (CVDs) are one of the global leading causes of concern due to the rising prevalence and consequence of mortality and disability with a heavy economic burden. The objective of the current study was to analyze the trend in CVD incidence, mortality, and mortality-to-incidence ratio (MIR) across the world over 28 years. The age-standardized CVD mortality and incidence rates were retrieved from the Global Burden of Disease (GBD) Study 2017 for both genders and different world super regions with available data every year during the period 1990–2017. Additionally, the Human Development Index was sourced from the United Nations Development Programme (UNDP) database for all countries at the same time interval. The marginal modeling approach was implemented to evaluate the mean trend of CVD incidence, mortality, and MIR for 195 countries and separately for developing and developed countries and also clarify the relationship between the indices and Human Development Index (HDI) from 1990 to 2017. The obtained estimates identified that the global mean trend of CVD incidence had an ascending trend until 1996 followed by a descending trend after this year. Nearly all of the countries experienced a significant declining mortality trend from 1990 to 2017. Likewise, the global mean MIR rate had a significant trivial decrement trend with a gentle slope of 0.004 over the time interval. As such, the reduction in incidence and mortality rates for developed countries was significantly faster than developing counterparts in the period 1990–2017 (p < 0.05). Nevertheless, the developing nations had a more rather shallow decrease in MIR compared to developed ones. Generally, the findings of this study revealed that there was an overall downward trend in CVD incidence and mortality rates, while the survival rate of CVD patients was rather stable. These results send a satisfactory message that global effort for controlling the CVD burden was quite successful. Nonetheless, there is an urgent need for more efforts to improve the survival rate of patients and lower the burden of this disease in some areas with an increasing trend of either incidence or mortality.
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