Analysis of the source of aggressiveness in gamecocks
Analysis of the source of aggressiveness in gamecocks
复制标题
斗鸡攻击性来源分析
DOI:
10.1038/s41598-020-63961-1
复制
发表时间:
2020
影响因子:
4.6
通讯作者:
Kobayashi Hiroyuki
中科院分区:
文献类型:
--
作者:
Komiyama Tomoyoshi;Yoshikawa Masanobu;Yokoyama Keiko;Kobayashi Hiroyuki
Although the fighting behaviour in gamecocks has evolved because of artificial selection, it is unknown whether the selection for aggressiveness affects neurotransmitter levels in the avian central nervous system. We sought to identify the source and origin of this trait. We collected the brain samples from 6 female Shamo gamecocks and 5 Shaver Brown chickens (control; bred for egg production). The midbrain levels of norepinephrine (NE) were significantly higher in Shamo gamecocks (P= 0.0087) than in the controls. Moreover, alleles encoding adrenergic receptors differed between the breeds in terms of response to NE. Gene mutations specific to Shamo and potentially associated with fighting behaviour were in sites T440N ofADRα1D; V296I ofADRα2A; and T44I, Q232R, and T277M ofADRβ2. The evolutionary analysis indicated that the ADRβ2 (T44I and Q232R) mutations were heritable in all Galliformes, whereas the T440N mutation of ADRα1D and V296I mutations of ADRα2A were unique to Shamo and originated by artificial selection. A high NE level may confer a selective advantage by enabling gamecocks to be aggressive and pain tolerant. Therefore, the strong fighting behaviour of Shamo has resulted from a combination of naturally inherited and mutant genes derived by artificial selection.
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DOI:
--
发表时间:
1995
期刊:
Pharmacology, Biochemistry and Behavior
影响因子:
--
作者:
Kinzo Matsumoto;K. Ojima;H. Watanabe
通讯作者:
H. Watanabe
影响因子:
64.8
作者:
T. Schantz;G. Göransson;Gunilla Andersson;Inger Fröberg;M. Grahn;A. Helgée;H. Wittzell
通讯作者:
H. Wittzell
影响因子:
3.7
作者:
Komiyama T;Hirokawa T;Sato K;Oka A;Kamiguchi H;Nagata E;Sakura H;Otsuka K;Kobayashi H
通讯作者:
Kobayashi H
影响因子:
3.8
作者:
Haller, J;Bakos, N;Liposits, Z
通讯作者:
Liposits, Z
影响因子:
3.3
作者:
C. Thode;J. Bock;K. Braun;M. Darlison
通讯作者:
C. Thode;J. Bock;K. Braun;M. Darlison