Stress and allergic diseases.

Stress and allergic diseases.
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DOI:
10.1016/j.iac.2010.09.009
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发表时间:
2011-02
影响因子:
2.6
通讯作者:
Marshall, Gailen D., Jr.
Marshall, Gailen D., Jr.
中科院分区:
医学3区
文献类型:
--
作者:
Dave, Ninabahen D.;Xiang, Lianbin;Rehm, Kristina E.;Marshall, Gailen D., Jr.

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过敏指的是一系列临床疾病,影响到世界上多达30%的人口。它的特点是产生过敏原特异性IgE,与肥大细胞结合,启动一系列分子和细胞事件,影响呼吸道(鼻炎和哮喘)、皮肤(皮炎、荨麻疹)和多种系统(过敏反应),包括花粉、霉菌孢子、动物皮屑、昆虫叮咬、食物和药物。潜在的病理生理学涉及免疫调节功能障碍,类似于在高度应激人群中注意到的。文中还讨论了干预潜力之间的关系。
Allergy describes a constellation of clinical diseases that affect up to 30% of the world’s population. It is characterized by production of allergen specific IgE which bind to mast cells and initiate a cascade of molecular and cellular events that affect the respiratory tract (rhinitis and asthma) skin (dermatitis, urticaria) and multi systems (anaphylaxis) to a variety of allergens including pollens, mold spores, animal danders, insect stings, foods and drugs. The underlying pathophysiology involves immunoregulatory dysfunctions similar to those noted in highly stressed populations. The relationships in terms of potentials for intervention are discussed.
DOI: 10.1097/00006842-199311000-00009
发表时间: 1993-11-01
影响因子: 3.3
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