Study on the resistance of severe acute respiratory syndrome-associated coronavirus.

Study on the resistance of severe acute respiratory syndrome-associated coronavirus.
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DOI:
10.1016/j.jviromet.2005.02.005
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发表时间:
2005-06
影响因子:
3.1
通讯作者:
Li JW
Li JW
中科院分区:
医学4区
文献类型:
--
作者:
Wang XW;Li JS;Jin M;Zhen B;Kong QX;Song N;Xiao WJ;Yin J;Wei W;Wang GJ;Si BY;Guo BZ;Liu C;Ou GR;Wang MN;Fang TY;Chao FH;Li JW

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在这项研究中,严重急性呼吸综合征相关冠状病毒(SARS-CoV)的持久性观察粪便,尿液和水。此外,还研究了次氯酸钠和二氧化氯对废水中SARS冠状病毒的灭活作用。体外实验表明,20 ℃下,病毒在医院废水、生活污水和脱氯自来水中只能存活2天,而在粪便中存活3天,在PBS中存活14天,在尿液中存活17天。然而,在4 °C下,SARS-CoV可以在废水中持续14天,在粪便或尿液中至少持续17天。SARS-CoV比大肠杆菌和f2噬菌体对消毒剂更敏感。游离氯被发现比二氧化氯更能抑制SARS冠状病毒。废水中游离余氯超过0.5mg/L(氯)或2.19mg/L(二氧化氯),可使SARS冠状病毒完全灭活,但不能完全灭活大肠杆菌。coli和F2噬菌体。
In this study, the persistence of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) was observed in feces, urine and water. In addition, the inactivation of SARS-CoV in wastewater with sodium hypochlorite and chlorine dioxide was also studied. In vitro experiments demonstrated that the virus could only persist for 2 days in hospital wastewater, domestic sewage and dechlorinated tap water, while 3 days in feces, 14 days in PBS and 17 days in urine at 20 °C. However, at 4 °C, the SARS-CoV could persist for 14 days in wastewater and at least 17 days in feces or urine. SARS-CoV is more susceptible to disinfectants than Escherichia coli and f2 phage. Free chlorine was found to inactivate SARS-CoV better than chlorine dioxide. Free residue chlorine over 0.5 mg/L for chlorine or 2.19 mg/L for chlorine dioxide in wastewater ensures complete inactivation of SARS-CoV while it does not inactivate completely E. coli and f2 phage.
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发表时间: 1999-05-01
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