Sex differences in ADHD symptom severity.

Sex differences in ADHD symptom severity.
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DOI:
10.1111/jcpp.12337
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发表时间:
2015-06
期刊:
Journal of child psychology and psychiatry, and allied disciplines
影响因子:
--
通讯作者:
Olson RK
Olson RK
中科院分区:
其他
文献类型:
--
作者:
Arnett AB;Pennington BF;Willcutt EG;DeFries JC;Olson RK

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男性患注意力缺陷多动障碍(ADHD)的比例高于女性。可能的解释包括真正的病因差异或人为因素。 2,332 名双胞胎和兄弟姐妹青少年参加了行为和认知测试。在随机选择的子样本中测试了症状严重程度分布差异的部分竞争模型、均值差异模型和方差差异模型。 Delta 方法用于通过处理速度、抑制和工作记忆来测试 ADHD 症状严重程度中性别差异的中介作用。均值差和方差差组合模型充分解释了 ADHD 症状严重程度的性别差异。认知内表型介导了 14% 的性别差异效应。 ADHD 症状严重程度的性别差异是合理的,可能是由于性别之间的遗传和认知能力不同所致。
Males show higher rates of attention deficit hyperactivity disorder (ADHD) than do females. Potential explanations include genuine etiological differences or artifact. 2,332 twin and sibling youth participated in behavioral and cognitive testing. Partially competing models of symptom severity distribution differences, the mean difference and variance difference models, were tested within a randomly selected subsample. The Delta method was used to test for mediation of sex differences in ADHD symptom severity by processing speed, inhibition and working memory. The combined mean difference and variance difference models fully explained the sex difference in ADHD symptom severity. Cognitive endophenotypes mediated 14% of the sex difference effect. The sex difference in ADHD symptom severity is valid and may be due to differing genetic and cognitive liabilities between the sexes.
DOI: 10.1080/15374416.2011.581621
发表时间: 2011
期刊: Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
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