Shaping the light for the investigation of depth-extended scattering media

Shaping the light for the investigation of depth-extended scattering media
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塑造光以研究深度扩展的散射介质

DOI:
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发表时间:
2018
期刊:
BiOS
影响因子:
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通讯作者:
M. Takeda
M. Takeda
中科院分区:
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文献类型:
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作者:
W. Osten;K. Frenner;G. Pedrini;A. Singh;J. Schindler;M. Takeda

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散射介质是包括相干和非相干原理在内的各种成像技术面临的一个持续挑战。受计算成像新方法的启发,在强大的计算机、空间光调制器、光源和探测器的支持下,各种新方法,从全息到飞行时间成像、相位共轭、使用迭代算法和相关技术的相位恢复,已经被引入并应用于不同类型的物体。然而,考虑到这一领域的明显进展,仍有一些问题有待研究,它们的解决也将为散射介质的研究和应用打开新的大门。特别是,这些悬而未决的问题包括将2d方法扩展到深度扩展物体的检查的可能性,直接使用散射介质作为复杂物体成像的简单工具,以及改进用于嵌入散射介质中的非相干辐射点的尺寸表征的相干检查技术。在本文中,我们展示了我们在应对这些挑战方面的最新发现。首先,我们描述了如何利用散射介质来探测深度扩展的物体。随后,我们扩展了这一方法,实现了一种新型显微镜,利用简单的散射板作为一种平面和非常规的成像透镜。最后,我们介绍了我们的剪切干涉仪与结构照明相结合,用于检索嵌入在散射介质中的荧光发光点的轴向位置。
Scattering media are an ongoing challenge for all kind of imaging technologies including coherent and incoherent principles. Inspired by new approaches of computational imaging and supported by the availability of powerful computers, spatial light modulators, light sources and detectors, a variety of new methods ranging from holography to time-of-flight imaging, phase conjugation, phase recovery using iterative algorithms and correlation techniques have been introduced and applied to different types of objects. However, considering the obvious progress in this field, several problems are still matter of investigation and their solution could open new doors for the inspection and application of scattering media as well. In particular, these open questions include the possibility of extending the 2d-approach to the inspection of depth-extended objects, the direct use of a scattering media as a simple tool for imaging of complex objects and the improvement of coherent inspection techniques for the dimensional characterization of incoherently radiating spots embedded in scattering media. In this paper we show our recent findings in coping with these challenges. First we describe how to explore depth-extended objects by means of a scattering media. Afterwards, we extend this approach by implementing a new type of microscope making use of a simple scatter plate as a kind of flat and unconventional imaging lens. Finally, we introduce our shearing interferometer in combination with structured illumination for retrieving the axial position of fluorescent light emitting spots embedded in scattering media.
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期刊: Scientific reports
影响因子: 4.6
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发表时间: 2008-02-01
期刊: NATURE PHOTONICS
影响因子: 35
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