A survey of human cancers for human papillomavirus DNA by filter hybridization

A survey of human cancers for human papillomavirus DNA by filter hybridization
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通过过滤杂交对人类癌症进行人乳头瘤病毒 DNA 调查

DOI:
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发表时间:
1987
期刊:
影响因子:
6.2
通讯作者:
A. Faras
A. Faras
中科院分区:
医学1区
文献类型:
--
作者:
R. Ostrow;D. Manias;Wendy J. Fong;K. Zachow;A. Faras

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我们使用低强度过滤杂交技术检测了217份不同人类恶性肿瘤组织样本中人乳头瘤病毒(HPV) DNA的存在。这些技术对HPV DNA探针与所有已知的人类和动物乳头瘤病毒DNA的交叉杂交都足够敏感。大约2%的被分析的癌症含有HPV DNA。其中包括肺癌、盲肠癌、舌癌和颈癌。4例癌症中有3例含有HPV‐16相关核苷酸序列。因此,除了先前的数据表明HPV DNA与某些皮肤和生殖道癌症的关联外,数据还表明,其他几种人类癌症也含有HPV相关的核苷酸序列。
We examined 217 tissue samples of various human malignancies for the presence of human papillomavirus (HPV) DNA using low‐stringency filter hybridization techniques. These techniques were sufficiently sensitive for crosshybridization of the HPV DNA probes to all the known types of papillomavirus DNAs, both human and animal. Approximately 2% of the cancers analyzed contained HPV DNA. These included carcinomas of the lung, cecum, tongue, and neck. Three of four cancers contained HPV‐16‐related nucleotide sequences. Thus, in addition to previous data demonstrating the association of HPV DNA with certain cancers of the skin and genital tract, data is presented that indicates that several additional human cancers also contain HPV‐related nucleotide sequences.
人乳头瘤病毒:病毒 DNA 序列的检测以及子宫颈化生和发育不良分子异质性的证据。
DOI: 10.1159/000149393
发表时间: 1983
期刊: Intervirology
影响因子: 4.6
作者:
Lancaster,WD;Kurman,RJ;Sanz,LE;Perry,S;Jenson,AB
通讯作者: Jenson,AB
DOI: --
发表时间: 1985
期刊: Cancer research
影响因子: 11.2
作者:
Fukushima,M;Okagaki,T;Twiggs,LB;Clark,BA;Zachow,KR;Ostrow,RS;Faras,AJ
通讯作者: Faras,AJ
肉类处理者皮肤疣中新型人乳头状瘤病毒的鉴定。
DOI: 10.1016/0042-6822(81)90524-9
发表时间: 1981
期刊: Virology
影响因子: 3.7
作者:
Ostrow,RS;Krzyzek,R;Pass,F;Faras,AJ
通讯作者: Faras,AJ
对人类癌症、正常组织和跖疣进行 1 型和 2 型人乳头瘤病毒 DNA 序列分析。
DOI: 10.1016/0042-6822(81)90019-2
发表时间: 1981
期刊: Virology
影响因子: 3.7
作者:
Green,M;Orth,G;Wold,WS;Sanders,PR;Mackey,JK;Favre,M;Croissant,O
通讯作者: Croissant,O