ImmPort, toward repurposing of open access immunological assay data for translational and clinical research.

ImmPort, toward repurposing of open access immunological assay data for translational and clinical research.
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DOI:
10.1038/sdata.2018.15
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发表时间:
2018-02-27
期刊:
影响因子:
9.8
通讯作者:
Butte AJ
Butte AJ
中科院分区:
综合性期刊2区
文献类型:
--
作者:
Bhattacharya S;Dunn P;Thomas CG;Smith B;Schaefer H;Chen J;Hu Z;Zalocusky KA;Shankar RD;Shen-Orr SS;Thomson E;Wiser J;Butte AJ

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免疫学研究人员开始探索免疫学数据的可重复性、重复使用和二次分析的可能性。开放获取数据集正在被应用于验证原始研究中使用的方法,利用研究进行荟萃分析,或产生新的假设。为了促进这些目标,为更广泛的研究社区创建了ImmPort数据库,以探索广泛的临床和基础研究数据以及相关发现。ImmPort生态系统由四个组件组成-私有数据,共享数据,数据分析和资源-用于数据存档,传播,分析和重用。迄今为止,已有300多项研究通过共享数据门户网站(www.immport.org/immport-open)免费提供,该门户网站允许研究数据重新利用,以加速将新见解转化为发现。
Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging studies for meta-analysis, or generating new hypotheses. To promote these goals, the ImmPort data repository was created for the broader research community to explore the wide spectrum of clinical and basic research data and associated findings. The ImmPort ecosystem consists of four components–Private Data, Shared Data, Data Analysis, and Resources—for data archiving, dissemination, analyses, and reuse. To date, more than 300 studies have been made freely available through the Shared Data portal (www.immport.org/immport-open), which allows research data to be repurposed to accelerate the translation of new insights into discoveries.
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