Phosphorelay control of phycobilisome biogenesis during complementary chromatic adaptation

Phosphorelay control of phycobilisome biogenesis during complementary chromatic adaptation
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互补色适应过程中藻胆体生物发生的磷中继控制

DOI:
--
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发表时间:
1997
影响因子:
3.7
通讯作者:
D. Kehoe
D. Kehoe
中科院分区:
生物学3区
文献类型:
--
作者:
A. Grossman;D. Kehoe

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对于一些蓝藻,光在环境中的光谱分布调节藻胆体或捕光天线复合物的特定多肽的合成。这个过程,称为互补色适应,是由一个复杂的双组分调节系统控制的。在这些途径中,磷酸化中继通常通过两个组氨酸和两个天冬氨酸残基发生。CCA突变体的产生和互补揭示了该途径的三个元件,一个假定的传感器RcaE和两个响应调节器RcaC和RcaF。RcaC是一个大的反应调节因子,包含两个输入结构域,一个DNA结合基序和一个假定的组氨酸磷酸受体结构域。RcaF是一个小的响应调节器,显然缺乏输出域。通路组分的排序将RcaE置于RcaF之前,RcaF置于RcaC之前。这种磷酸化受体电路是新颖的,因为它具有至少五个潜在的磷酸化受体结构域,而不是四个。
For some cyanobacteria, the spectral distribution of light in the environment regulates the synthesis of specific polypeptides of the phycobilisome or light harvesting antenna complex. This process, called complementary chromatic adaptation, is controlled by a complex type of two component regulatory system. In such pathways, phosphorelay typically occurs through two histidine and two aspartate residues. Generation and complementation of mutants in CCA have uncovered three elements of this pathway, a putative sensor, RcaE, and two response regulators, RcaC and RcaF. RcaC, a large response regulator, contains two input domains, a DNA binding motif and a putative histidine phosphoacceptor domain. RcaF is a small response regulator and apparently lacks an output domain. Ordering of the pathway components has placed RcaE before RcaF, and RcaF before RcaC. This phosphorelay circuitry is novel because it has, instead of four, at least five potential phosphoacceptor domains for signal transduction.
蛋白质天冬氨酸磷酸酶控制双组分信号转导系统的输出。
DOI: 10.1016/0168-9525(96)81420-x
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