Measuring the longitudinal relaxation time of GABA in vivo at 3 Tesla.
Measuring the longitudinal relaxation time of GABA in vivo at 3 Tesla.
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DOI:
10.1002/jmri.23817
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发表时间:
2013-04
影响因子:
4.4
通讯作者:
Edden, Richard A. E.
中科院分区:
文献类型:
--
作者:
Puts, Nicolaas A. J.;Barker, Peter B.;Edden, Richard A. E.
To measure the in vivo longitudinal relaxation time T1 of GABA at 3T. J-difference edited single-voxel magnetic resonance spectroscopy was used to isolate GABA signals. An increased echo time (80 ms) acquisition was used, accommodating the longer, more selective editing pulses required for symmetric editing-based suppression of co-edited macromolecular signal. Acquiring edited GABA measurements at a range of relaxation times in ten healthy participants, a saturation-recovery equation was used to model the integrated data. The longitudinal relaxation time of GABA was measured as T1,GABA = 1.31 ± 0.16 s. The method described has been successfully applied to measure the T1 of GABA in vivo at 3T.
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DOI:
10.1016/j.cub.2010.09.003
发表时间:
2010-10-12
期刊:
Current biology : CB
影响因子:
--
作者:
Boy F;Evans CJ;Edden RA;Singh KD;Husain M;Sumner P
通讯作者:
Sumner P
影响因子:
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作者:
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DOI:
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发表时间:
2011-11-16
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Puts NA;Edden RA;Evans CJ;McGlone F;McGonigle DJ
通讯作者:
McGonigle DJ
影响因子:
4.4
作者:
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通讯作者:
Barker, Peter B.
影响因子:
4.4
作者:
Evans, Christopher John;McGonigle, David John;Edden, Richard Anthony Edward
通讯作者:
Edden, Richard Anthony Edward