Spatial attention decorrelates intrinsic activity fluctuations in macaque area V4.
Spatial attention decorrelates intrinsic activity fluctuations in macaque area V4.
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DOI：
10.1016/j.neuron.2009.09.013
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发表时间：
2009-09-24
期刊：
影响因子：
16.2
通讯作者：
Reynolds, John H.
中科院分区：
文献类型：
--
作者：
Mitchell, Jude F.;Sundberg, Kristy A.;Reynolds, John H.
注意力通常会放大由任务相关刺激引起的神经元反应，同时减弱对任务无关干扰的反应。在这种情况下，视觉干扰构成了一个外部的噪声源，减少，以提高关注的信号质量。皮层内部的活动，刺激独立的持续相关波动，也可能作为任务无关的噪音。为了验证这一点，我们记录了猕猴执行注意力要求任务的V4区。神经元对相同重复刺激的放电是高度可变的。这种变异性的大部分来源于神经元群体中相关的频率的持续低频（<5Hz）波动。当注意力被引导到神经元感受野内的刺激时，这些相关的频率波动就会减少。与注意力依赖性的放电率增加相比，这种持续的皮层活动的注意力依赖性减少大大提高了汇集的神经信号的信噪比。
Attention typically amplifies neuronal responses evoked by task-relevant stimuli, while attenuating responses to task-irrelevant distracters. In this context, visual distracters constitute an external source of noise that is diminished to improve attended signal quality. Activity that is internal to the cortex itself, stimulus independent ongoing correlated fluctuations in firing, might also act as task-irrelevant noise. To examine this, we recorded from area V4 of macaques performing an attention-demanding task. The firing of neurons to identically repeated stimuli was highly variable. Much of this variability originates from ongoing low frequency (<5 Hz) fluctuations in rate correlated across the neuronal population. When attention is directed to a stimulus inside a neuron’s receptive field these correlated fluctuations in rate were reduced. This attention-dependent reduction of ongoing cortical activity improves the signal to noise ratio of pooled neural signals substantially more than attention-dependent increases in firing rate.
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DOI：
10.1126/science.1171402
发表时间：
2009-05-29
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Gregoriou GG;Gotts SJ;Zhou H;Desimone R
通讯作者：
Desimone R
影响因子：
16.2
作者：
Han, Feng;Caporale, Natalia;Dan, Yang
通讯作者：
Dan, Yang
影响因子：
64.8
作者：
Kenet, T;Bibitchkov, D;Arieli, A
通讯作者：
Arieli, A
影响因子：
2.5
作者：
Huang, Xin;Lisberger, Stephen G.
通讯作者：
Lisberger, Stephen G.
影响因子：
5.3
作者：
Bair, W;Zohary, E;Newsome, WT
通讯作者：
Newsome, WT