Bioactivity of Olive Oil Phenols in Neuroprotection.

Bioactivity of Olive Oil Phenols in Neuroprotection.
复制标题

橄榄油酚类在神经保护中的生物活性。

DOI:
10.3390/ijms18112230
复制
发表时间:
2017-10-25
影响因子:
5.6
通讯作者:
Hrelia S
Hrelia S
中科院分区:
生物学2区
文献类型:
--
作者:
Angeloni C;Malaguti M;Barbalace MC;Hrelia S

文献摘要

参考文献

被引文献

相似文献

神经系统疾病如中风、阿尔茨海默病和帕金森病与高发病率和死亡率相关,并且很少或没有有效的治疗选择。这些疾病具有共同的病理学特征,如诱导氧化应激、异常蛋白质聚集、扰乱Ca 2+稳态、兴奋性毒性、炎症和凋亡。大量证据支持地中海饮食在预防神经退行性变方面的有益作用。由于地中海饮食的特点是高消费特级初榨橄榄油,因此有人假设橄榄油,特别是其酚类,可能是地中海饮食的有益效果的原因。这篇综述提供了橄榄油和橄榄油酚在预防/抵消急性和慢性神经退行性疾病方面的有益特性的最新观点。
Neurological disorders such as stroke, Alzheimer’s and Parkinson’s diseases are associated with high morbidity and mortality, and few or no effective options are available for their treatment. These disorders share common pathological characteristics like the induction of oxidative stress, abnormal protein aggregation, perturbed Ca2+ homeostasis, excitotoxicity, inflammation and apoptosis. A large body of evidence supports the beneficial effects of the Mediterranean diet in preventing neurodegeneration. As the Mediterranean diet is characterized by a high consumption of extra-virgin olive oil it has been hypothesized that olive oil, and in particular its phenols, could be responsible for the beneficial effect of the Mediterranean diet. This review provides an updated vision of the beneficial properties of olive oil and olive oil phenols in preventing/counteracting both acute and chronic neurodegenerative diseases.
DOI: 10.1021/cn400024q
发表时间: 2013-06-01
影响因子: 5
作者:
Abuznait, Alaa H.;Qosa, Hisham;Kaddoumi, Amal
通讯作者: Kaddoumi, Amal
DOI: 10.1155/2014/238485
发表时间: 2014
影响因子: --
作者:
Angeloni C;Zambonin L;Hrelia S
通讯作者: Hrelia S
DOI: 10.1016/j.neuroscience.2017.03.059
发表时间: 2017-06-03
期刊: NEUROSCIENCE
影响因子: 3.3
作者:
Batarseh, Yazan S.;Mohamed, Loqman A.;Kaddoumi, Amal
通讯作者: Kaddoumi, Amal
DOI: 10.3390/ijms17081293
发表时间: 2016-08-09
影响因子: 5.6
作者:
Achour I;Arel-Dubeau AM;Renaud J;Legrand M;Attard E;Germain M;Martinoli MG
通讯作者: Martinoli MG
DOI: 10.1016/j.mrrev.2003.06.017
发表时间: 2003-11-01
影响因子: 5.3
作者:
Aruoma, OI;Bahorun, T;Jen, LS
通讯作者: Jen, LS