Frailty and acute coronary syndrome: A structured literature review.
Frailty and acute coronary syndrome: A structured literature review.
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DOI:
10.1177/2048872617700873
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发表时间:
2018-03
期刊:
影响因子:
--
通讯作者:
Gale CP
中科院分区:
文献类型:
--
作者:
Bebb O;Smith FG;Clegg A;Hall M;Gale CP
The health burden of acute coronary syndrome (ACS) and frailty is high, but the impact of frailty on ACS treatment and outcomes is uncertain. In this structured literature review, we investigated the relationship between frailty, ACS treatment and outcomes. Between 2000 and 2016, we identified only a small number of primary research studies investigating frailty and ACS care (n= 10). Frailty was independently associated with increased mortality following ACS (adjusted all-cause mortality hazard ratios for patients with frailty ranged from 1.54 – 5.39). Older people with frailty were significantly less likely to receive guideline-indicated ACS care, including percutaneous coronary intervention (PCI) (Rates ranged from 6.7% -43.7% vs. 30.4%-69.5%). Available data for PCI indicated a gap between treatment recommended by international guidelines and clinical practice. Further research is warranted to investigate methods for identifying frailty in the acute setting and opportunities for improving care among older people with frailty presenting with ACS.
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