Impacts of adverse childhood experiences on health, mental health, and substance use in early adulthood: a cohort study of an urban, minority sample in the U.S.
Impacts of adverse childhood experiences on health, mental health, and substance use in early adulthood: a cohort study of an urban, minority sample in the U.S.
复制标题
DOI：
10.1016/j.chiabu.2013.07.011
复制
发表时间：
2013-11
影响因子：
4.8
通讯作者：
Reynolds AJ
中科院分区：
文献类型：
--
作者：
Mersky JP;Topitzes J;Reynolds AJ
研究表明，不良的童年经历（ACE）会增加晚年与健康相关的不良后果的风险。关于ACE在成年早期或不同样本中的后果知之甚少。因此，我们调查了不同的ACE暴露对城市，少数民族样本的年轻人的影响。健康，心理健康和物质使用的结果进行了单独和汇总检查。还探讨了性别的潜在调节作用。数据来自芝加哥纵向研究，这是一项针对1979年或1980年出生的个人的小组调查。主效应分析采用多因素Logistic回归和OLS回归。性别差异进行了探讨分层分析，然后与全样本的交互作用的测试。结果证实，ACE与成年早期不良结局之间存在强有力的关联。更大程度的逆境与更差的自我评价健康和生活满意度，以及更频繁的抑郁症状，焦虑，吸烟，饮酒和大麻使用有关。累积的逆境也与跨领域的累积效应有关。例如，与没有ACE的个体相比，暴露于多种ACE的个体更可能有三个或更多个不良结局（OR范围= 2.75-10.15）和四个或更多个不良结局（OR范围= 3.93-15.18）。未检测到雄性和雌性之间的显著差异。考虑到ACE在成年早期的后果可能导致后来的发病率和死亡率，增加对预防ACE和改善其影响的计划和政策的投资是必要的。
Research has shown that adverse childhood experiences (ACEs) increase the risk of poor health-related outcomes in later life. Less is known about the consequences of ACEs in early adulthood or among diverse samples. Therefore, we investigated the impacts of differential exposure to ACEs on an urban, minority sample of young adults. Health, mental health, and substance use outcomes were examined alone and in aggregate. Potential moderating effects of sex were also explored. Data were derived from the Chicago Longitudinal Study, a panel investigation of individuals who were born in 1979 or 1980. Main-effect analyses were conducted with multivariate logistic and OLS regression. Sex differences were explored with stratified analysis, followed by tests of interaction effects with the full sample. Results confirmed that there was a robust association between ACEs and poor outcomes in early adulthood. Greater levels of adversity were associated with poorer self-rated health and life satisfaction, as well as more frequent depressive symptoms, anxiety, tobacco use, alcohol use, and marijuana use. Cumulative adversity also was associated with cumulative effects across domains. For instance, compared to individuals without an ACE, individuals exposed to multiple ACEs were more likely to have three or more poor outcomes (OR range = 2.75–10.15) and four or more poor outcomes (OR range = 3.93–15.18). No significant differences between males and females were detected. Given that the consequences of ACEs in early adulthood may lead to later morbidity and mortality, increased investment in programs and policies that prevent ACEs and ameliorate their impacts is warranted.
登录
查看更多内容
影响因子：
--
作者：
Danese, Andrea;Moffitt, Terrie E.;Harrington, HonaLee;Milne, Barry J.;Polanczyk, Guilherme;Pariante, Carmine M.;Poulton, Richie;Caspi, Avshalom
通讯作者：
Caspi, Avshalom
影响因子：
--
作者：
Dong, M;Dube, SR;Anda, RF
通讯作者：
Anda, RF
影响因子：
120.7
作者：
Anda, RF;Croft, JB;Giovino, GA
通讯作者：
Giovino, GA
影响因子：
8
作者：
Dube, SR;Felitti, VJ;Anda, RF
通讯作者：
Anda, RF
影响因子：
37.8
作者：
Dong, MX;Giles, WH;Anda, RF
通讯作者：
Anda, RF