Perspectives on immunoglobulins in colostrum and milk.
Perspectives on immunoglobulins in colostrum and milk.
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作者：
Hurley WL;Theil PK
免疫球蛋白形成在乳和初乳中发现的免疫活性的重要组分。当母亲将被动免疫传递给后代时，它们是免疫联系的核心。哺乳动物物种之间的转移机制各不相同。牛提供了一个容易获得的免疫丰富的初乳和牛奶大量，使这些分泌物的重要潜在来源的免疫产品，可能有利于人类。免疫乳是一个术语，用于描述一系列牛乳腺产品，这些产品已经过测试，可以抵抗几种人类疾病。使用初乳或乳汁作为免疫球蛋白的来源，无论是用于产生分泌物的物种的新生儿还是用于不同物种，都可以在分泌物中免疫球蛋白的类型、分泌免疫球蛋白的机制以及食用乳汁的新生儿或成人获得免疫益处的机制的背景下进行观察。当免疫球蛋白在乳中进行加工或在肠中进行消化时，其稳定性是评价乳免疫球蛋白价值的另一个考虑因素。本文综述了免疫球蛋白在初乳，牛奶和免疫牛奶中发现的基本知识。
Immunoglobulins form an important component of the immunological activity found in milk and colostrum. They are central to the immunological link that occurs when the mother transfers passive immunity to the offspring. The mechanism of transfer varies among mammalian species. Cattle provide a readily available immune rich colostrum and milk in large quantities, making those secretions important potential sources of immune products that may benefit humans. Immune milk is a term used to describe a range of products of the bovine mammary gland that have been tested against several human diseases. The use of colostrum or milk as a source of immunoglobulins, whether intended for the neonate of the species producing the secretion or for a different species, can be viewed in the context of the types of immunoglobulins in the secretion, the mechanisms by which the immunoglobulins are secreted, and the mechanisms by which the neonate or adult consuming the milk then gains immunological benefit. The stability of immunoglobulins as they undergo processing in the milk, or undergo digestion in the intestine, is an additional consideration for evaluating the value of milk immunoglobulins. This review summarizes the fundamental knowledge of immunoglobulins found in colostrum, milk, and immune milk.
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影响因子：
4.4
作者：
Cervenak, Judit;Bender, Balazs;Kacskovics, Imre
通讯作者：
Kacskovics, Imre
影响因子：
3.5
作者：
ALMASHIKHI, SA;NAKAI, S
通讯作者：
NAKAI, S
影响因子：
4.9
作者：
Carrillo-Conde, Brenda;Garza, Alicia;Narasimhan, Balaji
通讯作者：
Narasimhan, Balaji
DOI：
10.1016/b978-012491543-5/50107-8
发表时间：
2005-01-01
期刊：
MUCOSAL IMMUNOLOGY, 3RD EDITION
影响因子：
--
作者：
Butler, John E.;Kehrli, Marcus E., Jr.
通讯作者：
Kehrli, Marcus E., Jr.
影响因子：
5.5
作者：
Brandtzaeg, P
通讯作者：
Brandtzaeg, P