Self-referred patients in an aging male clinic: much more than androgen deficiency alone
Self-referred patients in an aging male clinic: much more than androgen deficiency alone
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老年男性诊所的自我转诊患者：不仅仅是雄激素缺乏
DOI：
10.1080/tam.6.3.157.165
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Jean Kaufman
中科院分区：
文献类型：
--
作者：
Guy T'sjoen;Els Feyen;P. D. Kuyper;Frank Comhaire;Jean Kaufman
在通过媒体对“andropause”主题进行宣传活动后，对81名连续自我介绍的患者进行了评价。就诊时，这些患者主诉可能与老年男性部分雄激素缺乏相关。测量激素参数，并完成特定的老年男性问卷，如老年男性雄激素缺乏症（ADAM）和老年男性症状（AMS）量表问卷。中位年龄为59岁（范围53-66岁），平均体重指数（BMI）为26.4 ± 3.3 kg/m2。平均睾酮为479.8 ± 149.0 ng/dl，平均游离睾酮为10.0 ± 3.0 ng/dl。只有7.1%的患者被诊断为“特发性”ADAM。大多数患者表现为勃起功能障碍。诊断出各种各样的疾病，包括血色病、微小和巨大泌乳素瘤、甲状腺功能减退症、良性前列腺肥大症和前列腺癌。AMS心理、躯体植物和性分量表的得分分别为12、16和13分，根据AMS分类，分别对应于重度、中度和重度主诉。AMS（总量表和分量表）与睾酮水平之间无相关性。AMS的躯体营养亚量表和BMI和insulin之间存在正相关性。总之，我们观察到，在一组selfreferred男性andropause是不是一个频繁的诊断，和其他病理需要解决需要多学科的方法。
Following an information campaign through the media on the subject of 'andropause', 81 consecutive self-referred patients were evaluated. At presentation these patients had complaints possibly related to partial androgen deficiency in the aging male. Hormonal parameters were measured and specific aging male questionnaires, such as Androgen Deficiency in Aging Male (ADAM) and Aging Males' Symptoms (AMS) scale questionnaires were completed. The median age was 59 (range 53-66) and mean body mass index (BMI) was 26.4 ± 3.3 kg/m2. Mean testosterone was 479.8 ± 149.0 ng/dl and mean free testosterone was 10.0 ± 3.0 ng/dl. Only 7.1% of all patients were diagnosed with 'idiopathic' ADAM. The majority of patients presented with erectile dysfunction. A wide variety of conditions were diagnosed, including hemo chromatosis, micro- and macroprolactinoma, hypothyroidism, benign prostate hypertrophism and prostate carcinoma. The scores of AMS psychological, somatovegetative and sexual subscales were 12, 16 and 13, according to AMS classification corresponding to severe, moderate and severe complaints, respectively. There was no correlation between AMS (total and subscales) and testosterone levels. A positive correlation between the somatovegetative subscale of the AMS and both BMI and insulin was found. In conclusion, we observed that in a group of selfreferred men andropause is not a frequent diagnosis, and other pathology needs to be addressed requiring a multidisciplinary approach.
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DOI：
10.1210/jcem.81.10.8855804
发表时间：
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期刊：
The Journal of clinical endocrinology and metabolism.
影响因子：
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LONGCOPE, C
DOI：
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DOI：
10.1210/jcem.84.2.5495
发表时间：
1999
期刊：
The Journal of clinical endocrinology and metabolism.
影响因子：
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作者：
Barrett-Connor,E;VonMuhlen,DG;Kritz-Silverstein,D
通讯作者：
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影响因子：
5
作者：
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通讯作者：
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