Dosimetric verification of a commercial inverse treatment planning system.
Dosimetric verification of a commercial inverse treatment planning system.
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商业逆向治疗计划系统的剂量测定验证。
DOI：
10.1088/0031-9155/44/2/013
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发表时间：
1999
影响因子：
3.5
通讯作者：
Boyer,AL
中科院分区：
文献类型：
--
作者：
Xing,L;Curran,B;Hill,R;Holmes,T;Ma,L;Forster,KM;Boyer,AL
商用三维(3D)反向治疗计划系统Corvus(Nomos Corporation，Sewickley，PA)最近推出。本文报告了我们将该系统投入临床应用的初步结果和经验。该系统使用模拟退火逆规划算法来计算强度调制场。强度调制场被分成可通过多叶准直器(MLC)通过一系列叶设置来传送的光束分布。治疗是使用计算机控制的MLC进行的。为了验证Corvus软件所使用的剂量计算算法，将单个矩形形场的剂量分布与水模扫描数据进行了比较。使用可放置在可旋转圆柱形水模中的电离室测量了预测将由多个场提供的剂量分布。电离室收集的积分电荷被用来检查单场和多场强度调制治疗在不同空间点的绝对剂量。所有测量点的实测值和预测值均在4%以内。另一组测量使用了一个带有射线胶片的立方体聚苯乙烯模型来记录辐射剂量分布。对胶片进行校准和扫描，以产生二维等剂量分布。最后，利用束流成像系统(BIS)测量了束视图中的强度调制X射线束方向图。然后将BIS测量的图像与基于MLC叶序列文件的理论计算进行比较，以验证处理将被准确地执行并且没有机器故障。所有病例均有很好的相关性(相关系数)。使用强度调制光束产生的治疗计划似乎适合于治疗邻近关键结构的不规则形状的肿瘤。结果表明，该系统具有临床放射治疗计划和实施的潜力，并可能在未来降低治疗的复杂性。
A commercial three-dimensional (3D) inverse treatment planning system, Corvus (Nomos Corporation, Sewickley, PA), was recently made available. This paper reports our preliminary results and experience with commissioning this system for clinical implementation. This system uses a simulated annealing inverse planning algorithm to calculate intensity-modulated fields. The intensity-modulated fields are divided into beam profiles that can be delivered by means of a sequence of leaf settings by a multileaf collimator (MLC). The treatments are delivered using a computer-controlled MLC. To test the dose calculation algorithm used by the Corvus software, the dose distributions for single rectangularly shaped fields were compared with water phantom scan data. The dose distributions predicted to be delivered by multiple fields were measured using an ion chamber that could be positioned in a rotatable cylindrical water phantom. Integrated charge collected by the ion chamber was used to check the absolute dose of single-and multifield intensity modulated treatments at various spatial points. The measured and predicted doses were found to agree to within 4% at all measurement points. Another set of measurements used a cubic polystyrene phantom with radiographic film to record the radiation dose distribution. The films were calibrated and scanned to yield two-dimensional isodose distributions. Finally, a beam imaging system (BIS) was used to measure the intensity-modulated x-ray beam patterns in the beam's-eye view. The BIS-measured images were then compared with a theoretical calculation based on the MLC leaf sequence files to verify that the treatment would be executed accurately and without machine faults. Excellent correlation (correlation coefficients) was found for all cases. Treatment plans generated using intensity-modulated beams appear to be suitable for treatment of irregularly shaped tumours adjacent to critical structures. The results indicated that the system has potential for clinical radiation treatment planning and delivery and may in the future reduce treatment complexity.
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影响因子：
3.8
作者：
MACKIE, TR;HOLMES, T;KINSELLA, T
通讯作者：
KINSELLA, T
用于三维光子剂量计算的有限尺寸笔形束模型。
DOI：
--
发表时间：
1992
期刊：
Medical Physics (Lancaster)
影响因子：
--
作者：
J. Bourland;E. Chaney
通讯作者：
E. Chaney
影响因子：
5.7
作者：
BRAHME, A
通讯作者：
BRAHME, A
调强适形疗法与传统外束立体定向放射外科系统治疗单个和多个颅内病变的比较。
DOI：
--
发表时间：
1996
期刊：
International Journal of Radiation Oncology, Biology, Physics
影响因子：
--
作者：
S. Woo;W. Grant;D. Bellezza;Robert Grossman;P. Gildenberg;L. Carpenter;M. Carol;E. Butler
通讯作者：
E. Butler
用于优化适形治疗的 3D 规划和交付系统
DOI：
--
发表时间：
1992
期刊：
影响因子：
--
作者：
M. Carol;H. Targovnik;Donald A. Smith;D. Cahill
通讯作者：
D. Cahill