Deposition features of inhaled viral droplets may lead to rapid secondary transmission of COVID-19.

Deposition features of inhaled viral droplets may lead to rapid secondary transmission of COVID-19.
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吸入病毒飞沫的沉积特征可能导致 COVID-19 的快速二次传播

DOI:
10.1016/j.jaerosci.2021.105745
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发表时间:
2021-05
影响因子:
4.5
通讯作者:
Tu J
Tu J
中科院分区:
环境科学与生态学3区
文献类型:
--
作者:
Shang Y;Tao Y;Dong J;He F;Tu J

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吸入的病毒飞沫可能会立即排出,并导致重新传播的升级。吸入病毒飞沫沉积位置的差异可能对病毒排出的概率有直接影响。本研究开发了一个数值模型,以估计区域特定的沉积分数的可吸入液滴(1-50米)在呼吸道。结果表明,上气道中的沉积分数高于下气道。特别是对于大于10 μ m的液滴,口/喉组合区域中相对高的沉积分数警告其容易通过随意的谈话/咳嗽传播。此外,考虑到液滴大小对病毒负载能力的影响,我们建立了一个相关模型来量化病毒驱逐危害的潜力,这表明在现有的传播机制之上,病毒传播存在放大的级联效应。因此,它强调了考虑从吸入的飞沫中即时排出的可能性的重要性,并且还意味着通过可以降低上呼吸道中的飞沫沉积的措施来限制快速二次传播的潜力。
Inhaled viral droplets may immediately be expelled and cause an escalating re-transmission. Differences in the deposition location of inhaled viral droplets may have a direct impact on the probability of virus expelling. This study develops a numerical model to estimate the region-specific deposition fractions for inhalable droplets (1–50 m) in respiratory airways. The results identified a higher deposition fraction in the upper airways than the lower airways. Particularly for droplets larger than 10 m, the relatively high deposition fraction in the oral/laryngeal combined region warns of its easy transmission through casual talking/coughing. Moreover, considering droplet sizes’ effect on virus loading capacity, we built a correlation model to quantify the potential of virus expelling hazards, which suggests an amplified cascade effect on virus transmission on top of the existing transmission mechanism. It therefore highlights the importance of considering the instant expelling possibilities from inhaled droplets, and also implies potentials in restricting a rapid secondary transmission by measures that can lower down droplet deposition in the upper airways.
DOI: 10.1021/acsnano.0c03252
发表时间: 2020-05-26
期刊: ACS NANO
影响因子: 17.1
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DOI: 10.1002/cnm.3215
发表时间: 2019-07-01
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