Redox Biology of Respiratory Viral Infections.
Redox Biology of Respiratory Viral Infections.
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DOI：
10.3390/v10080392
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发表时间：
2018-07-26
期刊：
影响因子：
--
通讯作者：
Ivanov AV
中科院分区：
文献类型：
--
作者：
Khomich OA;Kochetkov SN;Bartosch B;Ivanov AV
呼吸道病毒引起上呼吸道或下呼吸道感染，是世界上最流行的疾病--普通感冒的罪魁祸首。在许多情况下，普通感冒会导致严重的疾病，因为并发症，如发烧或肺炎。儿童、老年人和免疫抑制患者风险最高，需要快速诊断和治疗干预。然而，现有治疗方法的可用性和有效性因病毒而异。研究与呼吸道病毒感染相关的病理将对诊断、治疗方式和新疗法的开发至关重要。感染细胞氧化还原动态平衡的改变是与呼吸道病毒感染有关的关键事件之一，并与炎症和随后的组织损伤有关。我们的综述总结了目前关于不同呼吸道病毒引起的氧化还原动态平衡变化的知识。
Respiratory viruses cause infections of the upper or lower respiratory tract and they are responsible for the common cold—the most prevalent disease in the world. In many cases the common cold results in severe illness due to complications, such as fever or pneumonia. Children, old people, and immunosuppressed patients are at the highest risk and require fast diagnosis and therapeutic intervention. However, the availability and efficiencies of existing therapeutic approaches vary depending on the virus. Investigation of the pathologies that are associated with infection by respiratory viruses will be paramount for diagnosis, treatment modalities, and the development of new therapies. Changes in redox homeostasis in infected cells are one of the key events that is linked to infection with respiratory viruses and linked to inflammation and subsequent tissue damage. Our review summarizes current knowledge on changes to redox homeostasis, as induced by the different respiratory viruses.
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影响因子：
11.4
作者：
Cantu-Medellin N;Kelley EE
通讯作者：
Kelley EE
影响因子：
--
作者：
Cai Y;Li YF;Tang LP;Tsoi B;Chen M;Chen H;Chen XM;Tan RR;Kurihara H;He RR
通讯作者：
He RR
DOI：
10.1164/rccm.200804-535oc
发表时间：
2009-01-15
影响因子：
24.7
作者：
Cho, Hye-Youn;Imani, Farhad;Kleeberger, Steven R.
通讯作者：
Kleeberger, Steven R.
影响因子：
4.8
作者：
Bitzer, M;Armeanu, S;Lauer, UM
通讯作者：
Lauer, UM
影响因子：
2.7
作者：
Afonso CL;Amarasinghe GK;Bányai K;Bào Y;Basler CF;Bavari S;Bejerman N;Blasdell KR;Briand FX;Briese T;Bukreyev A;Calisher CH;Chandran K;Chéng J;Clawson AN;Collins PL;Dietzgen RG;Dolnik O;Domier LL;Dürrwald R;Dye JM;Easton AJ;Ebihara H;Farkas SL;Freitas-Astúa J;Formenty P;Fouchier RA;Fù Y;Ghedin E;Goodin MM;Hewson R;Horie M;Hyndman TH;Jiāng D;Kitajima EW;Kobinger GP;Kondo H;Kurath G;Lamb RA;Lenardon S;Leroy EM;Li CX;Lin XD;Liú L;Longdon B;Marton S;Maisner A;Mühlberger E;Netesov SV;Nowotny N;Patterson JL;Payne SL;Paweska JT;Randall RE;Rima BK;Rota P;Rubbenstroth D;Schwemmle M;Shi M;Smither SJ;Stenglein MD;Stone DM;Takada A;Terregino C;Tesh RB;Tian JH;Tomonaga K;Tordo N;Towner JS;Vasilakis N;Verbeek M;Volchkov VE;Wahl-Jensen V;Walsh JA;Walker PJ;Wang D;Wang LF;Wetzel T;Whitfield AE;Xiè JT;Yuen KY;Zhang YZ;Kuhn JH
通讯作者：
Kuhn JH