Pharyngeal critical pressure in children with mild sleep-disordered breathing.
Pharyngeal critical pressure in children with mild sleep-disordered breathing.
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轻度睡眠呼吸障碍儿童的咽部临界压力。
DOI：
10.1152/japplphysiol.01444.2005
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Bootzin,RR
中科院分区：
文献类型：
--
作者：
Fregosi,RF;Quan,SF;Morgan,WL;Goodwin,JL;Cabrera,R;Shareif,I;Fridel,KW;Bootzin,RR
There is evidence that narrowing or collapse of the pharynx can contribute to obstructive sleep-disordered breathing (SDB) in adults and children. However, studies in children have focused on those with relatively severe SDB who generally were recruited from sleep clinics. It is unclear whether children with mild SDB who primarily have hypopneas, and not frank apnea, also have more collapsible airways. We estimated airway collapsibility in 10 control subjects (9.4 ± 0.5 yr old; 1.9 ± 0.2 hypopneas/h) and 7 children with mild SDB (10.6 ± 0.5 yr old; 11.5 ± 0.1 hypopneas/h) during stable, non-rapid eye movement sleep. None of the subjects had clinically significant enlargement of the tonsils or adenoids, nor had any undergone previous tonsillectomy or adenoidectomy. Airway collapsibility was measured by brief (2-breath duration) and sudden reductions in pharyngeal pressure by connecting the breathing mask to a negative pressure source. Negative pressure applications ranging from −1 to −20 cmH2O were randomly applied in each subject while respiratory airflow and mask pressure were measured. Flow-pressure curves were constructed for each subject, and thex-intercept gave the pressure at zero flow, the so-called critical pressure of the upper airway (Pcrit). Pcrit was significantly higher in children with SDB than in controls (−10.8 ± 2.8 vs. −15.7 ± 1.2 cmH2O;P< 0.05). There were no significant differences in the slopes of the pressure-flow relations or in baseline airflow resistance. These data support the concept that intrinsic pharyngeal collapsibility contributes to mild SDB in children.
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影响因子：
9.6
作者：
Brunetti, L;Rana, S;Armenio, L
通讯作者：
Armenio, L
睡眠对呼吸控制的影响。
DOI：
--
发表时间：
1981
期刊：
影响因子：
--
作者：
Remmers Je
通讯作者：
Remmers Je
DOI：
10.1164/ajrccm.157.4.9702042
发表时间：
1998-04-01
影响因子：
24.7
作者：
Isono, S;Shimada, A;Nishino, T
通讯作者：
Nishino, T
阻塞性睡眠呼吸暂停综合征儿童阻塞性呼吸暂停发作时和结束时的膈肌和舌肌肌电活动
影响因子：
3.6
作者：
J. Praud;A. D'allest;M. Delaperche;S. Bobin;C. Gaultier
通讯作者：
C. Gaultier
影响因子：
3.3
作者：
SCHWARTZ, AR;SMITH, PL;PERMUTT, S
通讯作者：
PERMUTT, S