An interoceptive model of bulimia nervosa: A neurobiological systematic review.
An interoceptive model of bulimia nervosa: A neurobiological systematic review.
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DOI：
10.1016/j.jpsychires.2017.06.009
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发表时间：
2017-11
影响因子：
4.8
通讯作者：
Bohon C
中科院分区：
文献类型：
--
作者：
Klabunde M;Collado D;Bohon C
本研究的目的是探讨神经性贪食症（BN）的内感受感觉加工模型的神经生物学支持。为此，我们使用PRISMA指南对BN的内感受性感觉加工进行了系统的回顾。我们检索了PsychInfo， Pubmed和Web of Knowledge数据库，以确定生物学和行为学研究，以检查BN中的内感受性检测。在筛选了390篇文章并对符合纳入标准的文章进行了质量评估后，我们审查了41篇文章。我们发现全球内感受性感觉加工缺陷可能存在于BN中。具体来说，除了胃和疼痛处理障碍外，还存在异常的脑功能、结构和内感受神经网络连接的证据。这些结果表明，脑脊膜炎患者在恢复后仍存在整体内感受性感觉加工缺陷，可能存在神经生物学基础。味觉和心跳检测研究的数据尚无定论，但一些研究表明这些感觉域存在内感受性障碍。研究结果的差异似乎是由于方法上的差异。总之，内感受性感觉加工缺陷可能直接导致并解释了BN患者出现的各种症状。进一步检查内感受性感觉缺陷可以为BN患者的治疗提供信息。
The objective of our study was to examine the neurobiological support for an interoceptive sensory processing model of bulimia nervosa (BN). To do so, we conducted a systematic review of interoceptive sensory processing in BN, using the PRISMA guidelines. We searched PsychInfo, Pubmed, and Web of Knowledge databases to identify biological and behavioral studies that examine interoceptive detection in BN. After screening 390 articles for inclusion and conducting a quality assessment of articles that met inclusion criteria, we reviewed 41 articles. We found that global interoceptive sensory processing deficits may be present in BN. Specifically there is evidence of abnormal brain function, structure and connectivity in the interoceptive neural network, in addition to gastric and pain processing disturbances. These results suggest that there may be a neurobiological basis for global interoceptive sensory processing deficits in BN that remain after recovery. Data from taste and heart beat detection studies were inconclusive, yet some studies suggest interoceptive disturbances in these sensory domains. Discrepancies in findings appear to be due to methodological differences. In conclusion, interoceptive sensory processing deficits may directly contribute to and explain a variety of symptoms present in those with BN. Further examination of interoceptive sensory deficits could inform the development of treatments for those with BN.
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影响因子：
5.5
作者：
Fassino, S;Pieró, A;Rovera, GG
通讯作者：
Rovera, GG
影响因子：
5.5
作者：
Brand-Gothelf, Ayelet;Parush, Shula;Stein, Daniel
通讯作者：
Stein, Daniel
DOI：
10.1097/00005176-200307000-00006
发表时间：
2003-07-01
影响因子：
2.9
作者：
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通讯作者：
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影响因子：
7.1
作者：
DREWNOWSKI, A;HALMI, KA;SMITH, GP
通讯作者：
SMITH, GP
影响因子：
3.3
作者：
Cameron, OG
通讯作者：
Cameron, OG