Is there an epilepsy belt of high prevalence rate in China?
Is there an epilepsy belt of high prevalence rate in China?
复制标题
我国是否存在癫痫高发区？
DOI：
10.3389/fneur.2022.994305
复制
发表时间：
2022
影响因子：
3.4
通讯作者：
Jiang, Yongjun
中科院分区：
文献类型：
--
作者：
Wu, Li;Ye, Zeming;Li, Youfu;Luo, Ming;Li, Shaojun;Mi, Hongyan;Qiu, Zhihua;Jiang, Yongjun
癫痫是一种主要的神经系统疾病。本研究的目的是确定中国是否存在癫痫高发的病灶区域。系统回顾了1981年至2020年期间发表的所有调查中国癫痫患病率的研究。对地理位置、样本量、病例数、城市化率、人均国内生产总值（GDP）、<15岁人口比例和人均医疗保险进行了推导和分析。高患病率省级地区的标准定义为癫痫患病率高于中国癫痫平均患病率。共有60项研究提供了中国33个省级地区中29个地区癫痫患病率的数据。全国平均患病率为1.68/1000，其中12个省区符合癫痫高发区标准，构成了沿着中国第二、第三阶梯的癫痫带。癫痫带的患病率为331.9/10万，而非癫痫带的患病率为125.3/10万（P < 0.05）。令人惊讶的是，癫痫带内外的地区在样本量、病例数、城市化率、人均GDP、<15岁的百分比或人均医疗保险方面没有显著差异。在我国第二、第三阶梯线的沿着12个省区存在癫痫高发带。
Epilepsy is one of the leading neurological diseases. Our study is aimed to determine whether there is a focal region of high epilepsy prevalence in China. All studies published between 1981 and 2020 investigating the prevalence of epilepsy in China were systematically reviewed. The geographical location, sample size, number of cases, urbanization rate, gross domestic product (GDP) per capita, percentage of <15 years old, and medical insurance per capita were derived and analyzed. Criteria for a provincial region of high prevalence was defined as with higher epilepsy prevalence than the average prevalence of epilepsy in China. A total of 60 studies provided data on the prevalence of epilepsy in 29 of 33 provincial regions of China. The average prevalence in China was 1.68 per 1,000, and 12 provincial regions met our criteria for a region of high epilepsy prevalence and constitute an epilepsy belt ranging along the division between the second step and the third step of China. The prevalence in the epilepsy belt was 331.9 per 100,000 population compared with 125.3 per 100,000 in regions outside the belt (P < 0.05). Surprisingly, there was no significant difference in sample size, number of cases, urbanization rate, GDP per capita, percentage of <15 years old, or medical insurance per capita between the regions in and outside the epilepsy belt. An epilepsy belt of high prevalence exists in 12 provincial regions locating along the division between the second step and the third step of China.
影响因子：
3
作者：
Hu, Jia;Si, Yang;Chen, Xiao-fang
通讯作者：
Chen, Xiao-fang
影响因子：
2.2
作者：
Gu, Lian;Liang, Baoyun;Su, Li
通讯作者：
Su, Li
影响因子：
2.2
作者：
Chen, Chih-Chuan;Chen, Ta-Fu;Liou, Horng-Huei
通讯作者：
Liou, Horng-Huei