Vector composition, abundance, biting patterns and malaria transmission intensity in Madang, Papua New Guinea: assessment after 7 years of an LLIN-based malaria control programme.
Vector composition, abundance, biting patterns and malaria transmission intensity in Madang, Papua New Guinea: assessment after 7 years of an LLIN-based malaria control programme.
复制标题
DOI：
10.1186/s12936-021-04030-4
复制
发表时间：
2022-01-05
期刊：
影响因子：
3
通讯作者：
Walker ED
中科院分区：
文献类型：
--
作者：
Keven JB;Katusele M;Vinit R;Rodríguez-Rodríguez D;Hetzel MW;Robinson LJ;Laman M;Karl S;Walker ED
2009年，巴布亚新几内亚开始实施一项疟疾控制方案，分发长效驱虫蚊帐和青蒿素综合疗法。该方案实施后，病媒数量和疟疾传播强度大幅下降。这里报告的研究调查了这些减少是否在七年的持续努力后仍然存在。2016年9月至2017年3月期间，在马当省的四个村庄，利用人类着陆捕获和屏障屏障方法进行了通宵（18：00至06：00）蚊子收集。用分子生物学方法对按蚊进行了种属鉴定和子孢子感染间日疟原虫和恶性疟原虫的研究。病媒组成表示为村庄中不同物种的相对比例，病媒丰度表示为每个屏障夜晚和每人夜晚的蚊子数量。传播强度被量化为每人每晚子孢子感染性媒介叮咬的数量。存在五种按蚊，但不同村庄的病媒组成差异很大。在Bulal、Matukar和Wasab村，Koliensis按蚊是一种强嗜中性种，占所有按蚊的63.7-73.8%，但在Megiar村，Farauti按蚊是最普遍的种（97.6%）。病媒丰度因村庄而异（范围从2.8至72.3按蚊每屏幕夜和2.2-31.1按蚊每人夜），并在村庄内的空间。那些村庄的疟疾传播强度各不相同，数值范围为每人每晚0.03至0.5次感染性按蚊叮咬。大部分按蚊叮咬发生在室外（54.1-75.1%），其中相当大的比例（25.5-50.8%）发生在22：00之前。目前研究中的病媒丰度和传播强度估计值与2010-2012年在同一村庄的估计值相当或更高，表明方案效力受到阻碍。病媒的户外和早期叮咬行为是一些可能的解释因素。病媒组成、丰度和村庄之间及村庄内部分布的异质性对疟疾控制方案提出了挑战，在规划方案时必须加以考虑。在线版本包含补充材料，可通过10.1186/s12936-021-04030-4获得。
A malaria control programme based on distribution of long-lasting insecticidal bed nets (LLINs) and artemisinin combination therapy began in Papua New Guinea in 2009. After implementation of the programme, substantial reductions in vector abundance and malaria transmission intensity occurred. The research reported here investigated whether these reductions remained after seven years of sustained effort. All-night (18:00 to 06:00) mosquito collections were conducted using human landing catches and barrier screen methods in four villages of Madang Province between September 2016 and March 2017. Anopheles species identification and sporozoite infection with Plasmodium vivax and Plasmodium falciparum were determined with molecular methods. Vector composition was expressed as the relative proportion of different species in villages, and vector abundance was quantified as the number of mosquitoes per barrier screen-night and per person-night. Transmission intensity was quantified as the number of sporozoite-infective vector bites per person-night. Five Anopheles species were present, but vector composition varied greatly among villages. Anopheles koliensis, a strongly anthropophilic species was the most prevalent in Bulal, Matukar and Wasab villages, constituting 63.7–73.8% of all Anopheles, but in Megiar Anopheles farauti was the most prevalent species (97.6%). Vector abundance varied among villages (ranging from 2.8 to 72.3 Anopheles per screen-night and 2.2–31.1 Anopheles per person-night), and spatially within villages. Malaria transmission intensity varied among the villages, with values ranging from 0.03 to 0.5 infective Anopheles bites per person-night. Most (54.1–75.1%) of the Anopheles bites occurred outdoors, with a substantial proportion (25.5–50.8%) occurring before 22:00. The estimates of vector abundance and transmission intensity in the current study were comparable to or higher than estimates in the same villages in 2010–2012, indicating impeded programme effectiveness. Outdoor and early biting behaviours of vectors are some of the likely explanatory factors. Heterogeneity in vector composition, abundance and distribution among and within villages challenge malaria control programmes and must be considered when planning them. The online version contains supplementary material available at 10.1186/s12936-021-04030-4.
登录
查看更多内容
影响因子：
3.2
作者：
Davidson, Jenna R.;Sukowati, Supratman;Lobo, Neil F.
通讯作者：
Lobo, Neil F.
影响因子：
1.9
作者：
CHARLWOOD, JD;DAGORO, H;PARU, R
通讯作者：
PARU, R
DOI：
10.4269/ajtmh.1988.39.135
发表时间：
1988-08-01
影响因子：
3.3
作者：
BURKOT, TR;GRAVES, PM;HEYWOOD, PF
通讯作者：
HEYWOOD, PF
影响因子：
1.4
作者：
HASIBEDER, G;DYE, C
通讯作者：
DYE, C
影响因子：
3
作者：
Burkot, Thomas R.;Russell, Tanya L.;Lobo, Neil F.
通讯作者：
Lobo, Neil F.