Assessing everyday functioning in schizophrenia: not all informants seem equally informative.

Assessing everyday functioning in schizophrenia: not all informants seem equally informative.
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DOI:
10.1016/j.schres.2011.05.003
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发表时间:
2011-09
影响因子:
4.5
通讯作者:
Harvey, Philip D.
Harvey, Philip D.
中科院分区:
医学2区
文献类型:
--
作者:
Sabbag, Samir;Twamley, Elizabeth M.;Vella, Lea;Heaton, Robert K.;Patterson, Thomas L.;Harvey, Philip D.

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研究发现,精神分裂症患者的日常功能自我报告与其他被调查者的报告以及他们自己在认知和功能测试中的表现之间的相关性很低。然而,目前尚不清楚哪些线人最适合提供关于日常运作的准确报告。本研究检查了精神分裂症患者(n=193)的自我报告之间的趋同性,这些患者的真实世界功能由朋友或亲戚(n=154)或高接触临床医生(n=39)在6个功能状态评定量表中进行评定。此外,还计算了这些报告与患者在神经心理学测试和基于性能的功能能力测量中的表现之间的相关性。对于评价者之间的趋同,朋友或亲戚的线人和病人的报告显着相关的4/6的评级量表。对于较小样本的临床医生提供者,相关性在2/6尺度上是显著的。在病人的表现分数和功能评级之间的收敛性分析,只有1/12的患者报告和性能之间的相关性是显着的,而朋友或亲戚的报告也只与性能的一个评级量表。与此相反,临床医生报告的功能与患者的功能能力表现的4/6的评级量表和神经心理学测试的表现2/6。高接触临床医生似乎产生的日常功能,更密切地联系到病人的能力得分比朋友或亲戚的线人。随后的分析将确定朋友或亲戚线人之间是否存在差异。
Self reports of everyday functioning on the part of people with schizophrenia have been found to be poorly correlated with the reports of other informants and with their own performance of tests of cognition and functional abilities. However, it is not clear which informants are best for providing accurate reports of everyday functioning. This study examined the convergence between self-reports on the part of people with schizophrenia (n=193), who real-world functioning was rated by a friend or relative (n=154), or a high contact clinician (n=39) across 6 functional status rating scales. In addition, correlations between these reports and patient’s performance on neuropsychological tests and a performance-based measure of functional capacity were also calculated. For convergence between raters, friend or relative informants and patient reports were significantly correlated for 4/6 rating scales. For the smaller sample of clinician informants, the correlations were significant on 2/6 scales. In the analyses of convergence between patient performance scores and functioning ratings, only 1/12 correlations between patient report and performance were significant, while friend or relative reports also were only correlated with performance on one rating scale. In contrast, clinician reports of functioning were correlated with patients’ functional capacity performance on 4/6 rating scales and with neuropsychological test performance on 2/6. High contact clinicians appear to generate ratings of everyday functioning that are more closely linked to patients’ ability scores than friend or relative informants. Later analyses will determine if there are differences between friend or relative informants.
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