PHI-base in 2022: a multi-species phenotype database for Pathogen-Host Interactions.
PHI-base in 2022: a multi-species phenotype database for Pathogen-Host Interactions.
复制标题
2022年的PHI-base:病原体-宿主相互作用的多物种表型数据库。
DOI:
10.1093/nar/gkab1037
复制
发表时间:
2022-01-07
影响因子:
14.9
通讯作者:
Hammond-Kosack KE
中科院分区:
文献类型:
--
作者:
Urban M;Cuzick A;Seager J;Wood V;Rutherford K;Venkatesh SY;Sahu J;Iyer SV;Khamari L;De Silva N;Martinez MC;Pedro H;Yates AD;Hammond-Kosack KE
Since 2005, the Pathogen–Host Interactions Database (PHI-base) has manually curated experimentally verified pathogenicity, virulence and effector genes from fungal, bacterial and protist pathogens, which infect animal, plant, fish, insect and/or fungal hosts. PHI-base (www.phi-base.org) is devoted to the identification and presentation of phenotype information on pathogenicity and effector genes and their host interactions. Specific gene alterations that did not alter the in host interaction phenotype are also presented. PHI-base is invaluable for comparative analyses and for the discovery of candidate targets in medically and agronomically important species for intervention. Version 4.12 (September 2021) contains 4387 references, and provides information on 8411 genes from 279 pathogens, tested on 228 hosts in 18, 190 interactions. This provides a 24% increase in gene content since Version 4.8 (September 2019). Bacterial and fungal pathogens represent the majority of the interaction data, with a 54:46 split of entries, whilst protists, protozoa, nematodes and insects represent 3.6% of entries. Host species consist of approximately 54% plants and 46% others of medical, veterinary and/or environmental importance. PHI-base data is disseminated to UniProtKB, FungiDB and Ensembl Genomes. PHI-base will migrate to a new gene-centric version (version 5.0) in early 2022. This major development is briefly described.
登录
查看更多内容
影响因子:
4.5
作者:
Ames RM
通讯作者:
Ames RM
影响因子:
14.9
作者:
NCBI Resource Coordinators
通讯作者:
NCBI Resource Coordinators
DOI:
10.3390/jof4010039
发表时间:
2018-03-20
期刊:
Journal of fungi (Basel, Switzerland)
影响因子:
--
作者:
Basenko EY;Pulman JA;Shanmugasundram A;Harb OS;Crouch K;Starns D;Warrenfeltz S;Aurrecoechea C;Stoeckert CJ Jr;Kissinger JC;Roos DS;Hertz-Fowler C
通讯作者:
Hertz-Fowler C
影响因子:
64.8
作者:
Fisher, Matthew C.;Henk, Daniel. A.;Briggs, Cheryl J.;Brownstein, John S.;Madoff, Lawrence C.;McCraw, Sarah L.;Gurr, Sarah J.
通讯作者:
Gurr, Sarah J.
影响因子:
14.9
作者:
Hastings J;Owen G;Dekker A;Ennis M;Kale N;Muthukrishnan V;Turner S;Swainston N;Mendes P;Steinbeck C
通讯作者:
Steinbeck C