Methods for robust in vivo strain estimation in the carotid artery.
Methods for robust in vivo strain estimation in the carotid artery.
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DOI：
10.1088/0031-9155/57/22/7329
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发表时间：
2012-11-21
影响因子：
3.5
通讯作者：
Dempsey RJ
中科院分区：
文献类型：
--
作者：
McCormick M;Varghese T;Wang X;Mitchell C;Kliewer MA;Dempsey RJ
A hierarchical block-matching motion tracking algorithm for strain imaging is presented. Displacements are estimated with improved robustness and precision by utilizing a Bayesian regularization algorithm and an unbiased subsample interpolation technique. A modified least-squares strain estimator is proposed to estimate strain images from a noisy displacement input while addressing the motion discontinuity at the wall-lumen boundary. Methods to track deformation over the cardiac cycle incorporate a dynamic frame skip criterion to process data frames with sufficient deformation to produce high signal-to-noise displacement and strain images. Algorithms to accumulate displacement and/or strain on particles in a region of interest over the cardiac cycle are described. New methods to visualize and characterize the deformation measured with the full 2D strain tensor are presented. Initial results from patients imaged prior to carotid endarterectomy suggest that strain imaging detects conditions that are traditionally considered high risk including soft plaque composition, unstable morphology, abnormal hemodynamics and shear of plaque against tethering tissue can be exacerbated by neoangiogenesis. For example, a maximum absolute principal strain exceeding 0.2 is observed near calcified regions adjacent to turbulent flow, protrusion of the plaque into the arterial lumen and regions of low echogenicity associated with soft plaques. Non-invasive carotid strain imaging is therefore a potentially useful tool for detecting unstable carotid plaque.
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影响因子：
1.5
作者：
Ajduk, Marko;Pavic, Ladislav;Brkljacic, Boris
通讯作者：
Brkljacic, Boris
影响因子：
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作者：
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DOI：
10.1115/1.1800557
发表时间：
2004-10-01
影响因子：
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作者：
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通讯作者：
Regitnig, P
影响因子：
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作者：
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通讯作者：
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