Self-reported snoring frequency and incidence of cardiovascular disease: the Circulatory Risk in Communities Study (CIRCS).
Self-reported snoring frequency and incidence of cardiovascular disease: the Circulatory Risk in Communities Study (CIRCS).
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DOI：
10.2188/jea.je20110109
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发表时间：
2012
影响因子：
4.7
通讯作者：
CIRCS Investigators
中科院分区：
文献类型：
--
作者：
Nagayoshi M;Tanigawa T;Yamagishi K;Sakurai S;Kitamura A;Kiyama M;Okada T;Maeda K;Ohira T;Imano H;Sato S;Iso H;CIRCS Investigators
虽然在一些前瞻性研究中已经报道了打鼾和心血管疾病之间的联系，但来自亚洲人群的证据有限。本研究的目的是确定日本人自述的打鼾频率与心血管疾病发病率之间是否存在关联。研究对象是2350名男性和4163名女性，年龄在40到69岁之间，他们生活在日本的3个社区。所有受试者都参加了社区循环风险研究（CIRCS），随访6年。随访期间心血管疾病的发生率包括心肌梗死、心绞痛、心源性猝死和中风。在6年的随访期间，97名参与者（56名男性和41名女性）发生心血管事件。在对潜在的混杂因素进行调整后，自我报告的打鼾频率与女性心血管事件风险增加有关，而与男性无关。女性有时打鼾的心血管事件风险比（95% CI）为0.9(0.4-2.0)，每天打鼾的为2.5(1.0 - 6.1)，男性分别为0.7（0.3-1.3）和1.0（0.5-2.1）。进一步调整身体质量指数降低了女性的相关性；心血管事件的风险比分别为0.9（0.4-1.9）和2.1（0.9 - 5.4）。在日本女性中，自我报告的习惯性打鼾与心血管疾病风险增加有关。超重可能在一定程度上介导了这种关联。
Although associations between snoring and cardiovascular disease have been reported in several prospective studies, there is limited evidence from Asian populations. The objective of this study was to determine if there is an association between self-reported snoring frequency and the incidence of cardiovascular disease in Japanese. The subjects were 2350 men and 4163 women aged 40 to 69 years who lived in 3 communities in Japan. All subjects were participants in the Circulatory Risk in Communities Study (CIRCS) and were followed for 6 years. Incidence of cardiovascular disease during the follow-up period comprised events of myocardial infarction, angina pectoris, sudden cardiac death and stroke. During the 6-year follow-up period, 97 participants (56 men and 41 women) had cardiovascular events. After adjustment for potential confounding factors, self-reported snoring frequency was associated with an increased risk of cardiovascular events among women but not men. The hazard ratios (95% CI) for cardiovascular events were 0.9 (0.4–2.0) for sometimes snoring and 2.5 (1.0–6.1) for everyday snoring in women and 0.7 (0.3–1.3) and 1.0 (0.5–2.1), respectively, in men. Further adjustment for body mass index attenuated the association in women; the respective hazard ratios for cardiovascular events were 0.9 (0.4–1.9) and 2.1 (0.9–5.4). Self-reported habitual snoring was associated with increased risk of cardiovascular events among Japanese women. Overweight may partly mediate this association.
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影响因子：
3.8
作者：
Ciftci, TU;Kokturk, O;Bilgihan, A
通讯作者：
Bilgihan, A
影响因子：
2.5
作者：
Nagayoshi, Mako;Yamagishi, Kazumasa;Iso, Hiroyasu
通讯作者：
Iso, Hiroyasu
影响因子：
5.4
作者：
Noda, Hiroyuki;Iso, Hiroyasu;Tsugane, Shoichiro
通讯作者：
Tsugane, Shoichiro
影响因子：
5
作者：
Punjabi, NM;Shahar, E;Resnick, HE
通讯作者：
Resnick, HE
影响因子：
37.8
作者：
Gottlieb DJ;Yenokyan G;Newman AB;O'Connor GT;Punjabi NM;Quan SF;Redline S;Resnick HE;Tong EK;Diener-West M;Shahar E
通讯作者：
Shahar E