Comparative analysis of gene prediction tools for viral genome annotation
Comparative analysis of gene prediction tools for viral genome annotation
复制标题
病毒基因组注释的基因预测工具的比较分析
DOI:
10.1101/2021.12.11.472104
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发表时间:
2021
期刊:
影响因子:
--
通讯作者:
González-Tortuero E
中科院分区:
文献类型:
--
作者:
González-Tortuero E
The number of newly available viral genomes and metagenomes has increased exponentially since the 12 development of high throughput sequencing platforms and genome analysis tools. Bioinformatic 13 annotation pipelines are largely based on open reading frame (ORF) calling software, which identifies genes 14 independently of the sequence taxonomical background. Although ORF-calling programs provide a rapid 15 genome annotation, they can misidentify ORFs and start codons; errors that might be perpetuated and 16 propagated over time. This study evaluated the performance of multiple ORF-calling programs for viral 17 genome annotation against the complete RefSeq viral database. Programs outputs varied when considering 18 the viral nucleic acid type versus the viral host. According to the number of ORFs, Prodigal and 19
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影响因子:
3
作者:
Shean, Ryan C.;Makhsous, Negar;Greninger, Alexander L.
通讯作者:
Greninger, Alexander L.
影响因子:
14.9
作者:
Bao, Yiming;Bolotov, Pavel;Dernovoy, Dmitry;Kiryutin, Boris;Tatusova, Tatiana
通讯作者:
Tatusova, Tatiana
影响因子:
--
作者:
G. Bornkamm;C. Des̀granges;L. Gissmann
通讯作者:
L. Gissmann
影响因子:
14.9
作者:
Wang S;Sundaram JP;Stockwell TB
通讯作者:
Stockwell TB
影响因子:
5.3
作者:
Pace J;Youens-Clark K;Freeman C;Hurwitz B;Van Doorslaer K
通讯作者:
Van Doorslaer K