Bacteriophage-Based Bacterial Wilt Biocontrol for an Environmentally Sustainable Agriculture.

Bacteriophage-Based Bacterial Wilt Biocontrol for an Environmentally Sustainable Agriculture.
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DOI:
10.3389/fpls.2017.01218
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发表时间:
2017
影响因子:
5.6
通讯作者:
Biosca EG
Biosca EG
中科院分区:
生物学2区
文献类型:
--
作者:
Álvarez B;Biosca EG

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番茄青枯病由番茄青枯病菌、假番茄青枯病菌和青枯病菌引起。印度尼西亚病(原R. solanacearum)是世界上最重要的植物病害之一,严重影响大量作物和观赏植物。用非生物方法控制青枯病的困难与有效性、细菌耐药性和环境影响有关。另外,已经实施了许多生物防治战略,这些战略具有环境友好的优点。细菌性枯萎病生物防治的进展包括对基于噬菌体的治疗越来越感兴趣,这是一种有前途的重新出现的策略。对青枯病病原菌的噬菌体已有裂解或溶原作用的描述,但它们已被证明对属pseudosolanacearum和/或syzygii亚种的菌株有活性。其中只有2种在植物中表现出成功的生物防治潜力。尽管在这个主题上发表了三项专利,但到目前为止,还没有基于噬菌体的产品商业化。因此,将有效的噬菌体纳入综合管理计划以有效地对抗田间细菌性枯萎病,仍有许多工作要做。
Bacterial wilt diseases caused by Ralstonia solanacearum, R. pseudosolanacearum, and R. syzygii subsp. indonesiensis (former R. solanacearum species complex) are among the most important plant diseases worldwide, severely affecting a high number of crops and ornamentals. Difficulties of bacterial wilt control by non-biological methods are related to effectiveness, bacterial resistance and environmental impact. Alternatively, a great many biocontrol strategies have been carried out, with the advantage of being environmentally friendly. Advances in bacterial wilt biocontrol include an increasing interest in bacteriophage-based treatments as a promising re-emerging strategy. Bacteriophages against the bacterial wilt pathogens have been described with either lytic or lysogenic effect but, they were proved to be active against strains belonging to R. pseudosolanacearum and/or R. syzygii subsp. indonesiensis, not to the present R. solanacearum species, and only two of them demonstrated successful biocontrol potential in planta. Despite the publication of three patents on the topic, until now no bacteriophage-based product is commercially available. Therefore, there is still much to be done to incorporate valid bacteriophages in an integrated management program to effectively fight bacterial wilt in the field.
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