Sensorimotor transformation underlying odor-modulated locomotion in walking Drosophila.
Sensorimotor transformation underlying odor-modulated locomotion in walking Drosophila.
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果蝇行走中的气味调节运动的基础感官转化。
DOI:
10.1038/s41467-023-42613-8
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发表时间:
2023-10-26
影响因子:
16.6
通讯作者:
Bhandawat, Vikas
中科院分区:
文献类型:
--
作者:
Tao, Liangyu;Wechsler, Samuel P.;Bhandawat, Vikas
Most real-world behaviors – such as odor-guided locomotion - are performed with incomplete information. Activity in olfactory receptor neuron (ORN) classes provides information about odor identity but not the location of its source. In this study, we investigate the sensorimotor transformation that relates ORN activation to locomotion changes in Drosophila by optogenetically activating different combinations of ORN classes and measuring the resulting changes in locomotion. Three features describe this sensorimotor transformation: First, locomotion depends on both the instantaneous firing frequency (f) and its change (df); the two together serve as a short-term memory that allows the fly to adapt its motor program to sensory context automatically. Second, the mapping between (f, df) and locomotor parameters such as speed or curvature is distinct for each pattern of activated ORNs. Finally, the sensorimotor mapping changes with time after odor exposure, allowing information integration over a longer timescale. Animals find and stay close to resources by altering their locomotion in response to odors that signal resources. Here the authors identify, using Drosophila locomotion in response to odor, a simple strategy that adapts its motor program to sensory context automatically.
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DOI:
10.1098/rstb.2007.2054
发表时间:
2007-09-29
影响因子:
6.3
作者:
Cisek, Paul
通讯作者:
Cisek, Paul
影响因子:
7.7
作者:
Dolan, Michael-John;Frechter, Shahar;Jefferis, Gregory S. X. E.
通讯作者:
Jefferis, Gregory S. X. E.
影响因子:
9.2
作者:
Corfas, Roman A.;Sharma, Tarun;Dickinson, Michael H.
通讯作者:
Dickinson, Michael H.
影响因子:
1.7
作者:
Bergerot, Benjamin;Tournant, Pierline;Foltete, Jean-Christophe
通讯作者:
Foltete, Jean-Christophe
影响因子:
64.5
作者:
Cohn R;Morantte I;Ruta V
通讯作者:
Ruta V