Dual skin testing with Mycobacterium avium sensitin and purified protein derivative: an open study of patients with M. avium complex infection or tuberculosis.
Dual skin testing with Mycobacterium avium sensitin and purified protein derivative: an open study of patients with M. avium complex infection or tuberculosis.
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使用鸟分枝杆菌敏感素和纯化蛋白衍生物进行双重皮肤测试:对鸟分枝杆菌复合感染或结核病患者的开放研究。
DOI:
10.1093/clinids/19.1.15
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发表时间:
1994
期刊:
影响因子:
--
通讯作者:
Barber,TW
中科院分区:
文献类型:
--
作者:
vonReyn,CF;Green,PA;McCormick,D;Huitt,GA;Marsh,BJ;Magnusson,M;Barber,TW
The sensitivity and specificity of dual mycobacterial skin testing were assessed in an unblinded study of 22 patients with culture-confirmedMycobacterium aviumcomplex (MAC) infection and 20 patients with culture-confirmedMycobacterium tuberculosisinfection. Intradermal skin tests were performed with 0.1 mL ofM. aviumsensitin, 0.1 mL of PPD (purified protein derivative), and two control antigens (mumps andCandida). All patients withM. tuberculosisinfection reacted to the skin tests; the mean reaction size was 19.7 ± 1.4 mm when PPD was administered and 10.3 ± 1.5 mm whenM. aviumsensitin was administered. Four patients with MAC were anergic; for the remaining 18, mean reactions of 15.2 ± 1.4 mm toM. aviumsensitin and 4.3 ± 1.3 mm to PPD were noted. A skin test was defined asM. avium-dominant or PPD (M. tuberculosis) -dominant if there was a minimum reaction size of ⩾5 mm to the given species, and the reaction to the given species was ⩾3 mm greater than the reaction to the heterologous species. Dominant skin test reactions were present in 18 (90%) of 20 patients withM. tuberculosisand 15 (83%) of 18 nonanergic patients with MAC. The specificity of dominant skin tests was 100% for infection withM. tuberculosisand 100% for infection with MAC.M. avium-dominant skin tests identify subjects with prior MAC infection and distinguish them from patients withM. tuberculosisinfection.
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DOI:
10.1016/0962-8479(92)90144-9
发表时间:
1992
期刊:
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
影响因子:
--
作者:
S. Morris;J. Mackall;A. Malik;D. Rouse;S. Chaparas
通讯作者:
S. Chaparas
DOI:
10.1164/ajrccm/145.5.1160
发表时间:
1992
期刊:
The American review of respiratory disease
影响因子:
--
作者:
R. Huebner;Maybelle F. Schein;G. Cauthen;L. Geiter;Merle J. Selin;R. Good;R. O'brien
通讯作者:
R. O'brien
影响因子:
158.5
作者:
PRINCE, DS;PETERSON, DD;FISH, JE
通讯作者:
FISH, JE
DOI:
10.1093/clinids/12.5.760
发表时间:
1990
期刊:
Reviews of infectious diseases
影响因子:
--
作者:
Mark Lillo;Silva Orengo;P. Cernoch;Richard L. Harris
通讯作者:
Richard L. Harris
影响因子:
--
作者:
A. Margileth;R. Chandra;R. Altman
通讯作者:
R. Altman