Ambient temperature and cardiovascular mortality: a systematic review and meta-analysis.

Ambient temperature and cardiovascular mortality: a systematic review and meta-analysis.
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DOI:
10.7717/peerj.3574
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发表时间:
2017
期刊:
影响因子:
2.7
通讯作者:
Yekaninejad MS
Yekaninejad MS
中科院分区:
生物学3区
文献类型:
--
作者:
Moghadamnia MT;Ardalan A;Mesdaghinia A;Keshtkar A;Naddafi K;Yekaninejad MS

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我们的研究旨在通过系统回顾和荟萃分析来确定和量化冷热暴露与心血管死亡风险之间的关系。根据系统性综述和荟萃分析的首选报告项目(PRISMA)指南进行系统性综述和荟萃分析。在MEDLINE、Web of Science和Scopus数据库中检索了2000年1月至2015年底关于体温和心血管死亡率的同行评议研究。分别计算热暴露和冷暴露的短期效应的合并效应量。此外,我们评估了温度-心血管死亡率的剂量-反应关系的变化单位的纬度,经度,滞后天和年平均温度的元回归。筛选标题、摘要和全文后,共26篇文献纳入荟萃分析。冷暴露和热暴露的心血管死亡风险分别增加5%(RR,1.055; 95% CI [1.050 - 1.060])和1.3%(RR,1.013; 95% CI [1.011 - 1.015])。冷暴露和热暴露对男性心血管死亡风险的短期影响分别为3.8%(RR,1.038; 95% CI [1.034 - 1.043])和1.1%(RR,1.011; 95% CI [1.009 - 1.013])。此外,冷暴露和热暴露对女性心血管死亡风险的影响分别为4.1%(RR,1.041; 95% CI [1.037 - 1.045])和1.4%(RR,1.014; 95% CI [1.011 - 1.017])。在老年人中,热暴露和冷暴露分别增加8.1%和6%。在寒冷的温度下,心血管死亡的最大风险是在14个滞后天(RR,1.09; 95%CI [1.07 - 1.010]),在炎热的温度下,在7个滞后天(RR,1.14; 95%CI [1.09 - 1.17])。结果表明,冷暴露纬度和经度与心血管死亡率呈显著的剂量-反应关系,冷暴露纬度和经度越高,心血管死亡率越高,其危险性分别为0.2%,95%CI [0.006 - 0.035]和0.07%,95%CI [0.0003 - 0.014]。热暴露纬度每升高一度,心血管死亡风险增加(0.07%,95%CI [0.0008 - 0.124])。研究结果表明,环境温度的升高和降低与心血管死亡率有关。为预防与温度相关的死亡,应针对心血管疾病患者和老年人。该综述已在PROSPERO注册(注册号CRD 42016037673)。
Our study aims at identifying and quantifying the relationship between the cold and heat exposure and the risk of cardiovascular mortality through a systematic review and meta-analysis. A systematic review and meta-analysis were conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. Peer-reviewed studies about the temperature and cardiovascular mortality were retrieved in the MEDLINE, Web of Science, and Scopus databases from January 2000 up to the end of 2015. The pooled effect sizes of short-term effect were calculated for the heat exposure and cold exposure separately. Also, we assessed the dose–response relationship of temperature-cardiovascular mortality by a change in units of latitudes, longitude, lag days and annual mean temperature by meta-regression. After screening the titles, abstracts and full texts, a total of 26 articles were included in the meta-analysis. The risk of cardiovascular mortality increased by 5% (RR, 1.055; 95% CI [1.050–1.060]) for the cold exposure and 1.3% (RR, 1.013; 95% CI [1.011–1.015]) for the heat exposure. The short-term effects of cold and heat exposure on the risk of cardiovascular mortality in males were 3.8% (RR, 1.038; 95% CI [1.034–1.043]) and 1.1%( RR, 1.011; 95% CI [1.009–1.013]) respectively. Moreover, the effects of cold and heat exposure on risk of cardiovascular mortality in females were 4.1% (RR, 1.041; 95% CI [1.037–1.045]) and 1.4% (RR, 1.014; 95% CI [1.011–1.017]) respectively. In the elderly, it was at an 8.1% increase and a 6% increase in the heat and cold exposure, respectively. The greatest risk of cardiovascular mortality in cold temperature was in the 14 lag days (RR, 1.09; 95% CI [1.07–1.010]) and in hot temperatures in the seven lag days (RR, 1.14; 95% CI [1.09–1.17]). The significant dose–response relationship of latitude and longitude in cold exposure with cardiovascular mortality was found. The results showed that the risk of cardiovascular mortality increased with each degree increased significantly in latitude and longitude in cold exposure (0.2%, 95% CI [0.006–0.035]) and (0.07%, 95% CI [0.0003–0.014]) respectively. The risk of cardiovascular mortality increased with each degree increase in latitude in heat exposure (0.07%, 95% CI [0.0008–0.124]). Our findings indicate that the increase and decrease in ambient temperature had a relationship with the cardiovascular mortality. To prevent the temperature- related mortality, persons with cardiovascular disease and the elderly should be targeted. The review has been registered with PROSPERO (registration number CRD42016037673).
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