Staphylococcus lugdunensis Bacteremia with an Infected Aortic Thrombus in a Preterm Infant.
Staphylococcus lugdunensis Bacteremia with an Infected Aortic Thrombus in a Preterm Infant.
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DOI：
10.3390/children9010046
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发表时间：
2022-01-02
期刊：
影响因子：
--
通讯作者：
Chandrasekharan P
中科院分区：
文献类型：
--
作者：
Mani S;Chandrasekharan P
卢敦氏葡萄球菌是早产儿迟发性败血症的罕见原因。据我们所知，我们报告了第四例男性早产儿，他因卢顿葡萄球菌继发持续菌血症而发展为暴发性迟发性败血症，继发于感染的主动脉血栓，经两种阳性血培养证实。我们的患者是一个极低出生体重生长受限的婴儿，在怀孕27周时出生，最初需要脐动脉导管来监测血压和血气。这名新生儿的病程并发严重呼吸窘迫综合征，演变为慢性肺部疾病，并伴有多次气管炎发作。血流动力学方面，婴儿有明显的动脉导管未闭，并有一次内科坏死性小肠结肠炎发作，随后是卢顿葡萄球菌败血症。他被诊断出患有感染的主动脉血栓，可能是导致持续性菌血症的隐匿性病灶。经过6周的静脉注射抗生素疗程和4周的抗凝治疗疗程后，婴儿出现反应并康复，没有并发症。
Staphylococcus lugdunensis is a rare cause of late-onset sepsis in preterm infants. To our best knowledge, we report the fourth case of a male preterm infant who developed fulminant late-onset sepsis due to Staphylococcus lugdunensis with persistent bacteremia secondary to an infected aortic thrombus confirmed with two positive blood cultures. Our patient was an extremely low birth weight growth-restricted infant born at 27 weeks gestation and initially required an umbilical arterial catheter for blood pressure and blood gas monitoring. The course of this neonate was complicated by severe respiratory distress syndrome that evolved into chronic lung disease along with multiple episodes of tracheitis. Hemodynamically, the infant had a significant patent ductus arteriosus, and an episode of medical necrotizing enterocolitis followed by Staphylococcus lugdunensis septicemia. He was diagnosed with an infected aortic thrombus, probably the occult focus responsible for the persistent bacteremia. After a 6-week course of intravenous antibiotics and 4-week course of anticoagulant therapy, the infant responded and recovered without complications.
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影响因子：
3.6
作者：
Letouzey M;Foix-L'Hélias L;Torchin H;Mitha A;Morgan AS;Zeitlin J;Kayem G;Maisonneuve E;Delorme P;Khoshnood B;Kaminski M;Ancel PY;Boileau P;Lorthe E;EPIPAGE-2 Working Group on Infections
通讯作者：
EPIPAGE-2 Working Group on Infections
影响因子：
0.7
作者：
Elliott, SP;Yogev, R;Shulman, ST
通讯作者：
Shulman, ST
影响因子：
6.4
作者：
Liesenborghs, Laurens;Peetermans, Marijke;Verhamme, Peter
通讯作者：
Verhamme, Peter
影响因子：
5.1
作者：
Saracco, Paola;Bagna, Rossana;Simioni, Paolo
通讯作者：
Simioni, Paolo
影响因子：
3.6
作者：
Sotutu, V;Carapetis, J;Curtis, N
通讯作者：
Curtis, N