Prevalence Trends of Site-Specific Osteoarthritis From 1990 to 2019: Findings From the Global Burden of Disease Study 2019.

Prevalence Trends of Site-Specific Osteoarthritis From 1990 to 2019: Findings From the Global Burden of Disease Study 2019.
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1990 年至 2019 年部位特异性骨关节炎的患病率趋势:2019 年全球疾病负担研究的结果。

DOI:
10.1002/art.42089
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发表时间:
2022-07
影响因子:
13.3
通讯作者:
Guo, Ai
Guo, Ai
中科院分区:
医学1区
文献类型:
--
作者:
Long, Huibin;Liu, Qiang;Yin, Heyong;Wang, Kai;Diao, Naicheng;Zhang, Yuqing;Lin, Jianhao;Guo, Ai

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估计系统性和解剖部位特异性年龄标准化患病率(ASR),并分析全球、地区和国家层面骨关节炎(OA)的长期趋势。数据来自2019年全球疾病负担研究。根据年龄组、性别、地区、国家和领土以及涉及的关节,使用ASR及其估计的年百分比变化(EAPC)来描述OA的长期趋势。从全球来看,OA的流行病例增加了113.25%,从1990年的2.4751亿增加到2019年的5.2781亿。1990年ASR为6173.38/10万,2019年为6348.25/10万,年均增长0.12%(95%置信区间[95%CI] 0.11%,0.14%)。膝关节、髋关节和其他关节OA的ASR增加,但手的ASR降低,EAPC分别为0.32(95% CI 0.29,0.34)、0.28(95% CI 0.26,0.31)、0.18(95% CI 0.18,0.19)和−0.36(95% CI −0.38,−0.33)。OA患病率随着年龄的增长而增加,并显示女性占优势,地理多样性和解剖部位的差异。膝关节OA对总体负担的贡献最大,而髋关节OA在大多数地区的EAPC最高。在过去的几十年里,OA一直是全球主要的公共卫生问题。OA的患病率随着地理位置和受累关节的不同而增加和多样化。预防和早期治疗是减轻OA日益加重的负担的关键。
To estimate systematic and anatomic site–specific age‐standardized prevalence rates (ASRs) and analyze the secular trends of osteoarthritis (OA) at global, regional, and national levels. Data were derived from the Global Burden of Disease Study 2019. ASRs and their estimated annual percentage changes (EAPCs) were used to describe the secular trends of OA according to age group, sex, region, country, and territory, as well as the joints involved. Globally, prevalent cases of OA increased by 113.25%, from 247.51 million in 1990 to 527.81 million in 2019. ASRs were 6,173.38 per 100,000 in 1990 and 6,348.25 per 100,000 in 2019, with an average annual increase of 0.12% (95% confidence interval [95% CI] 0.11%, 0.14%). The ASR of OA increased for the knee, hip, and other joints, but decreased for the hand, with EAPCs of 0.32 (95% CI 0.29, 0.34), 0.28 (95% CI 0.26, 0.31), 0.18 (95% CI 0.18, 0.19), and −0.36 (95% CI −0.38, −0.33), respectively. OA prevalence increased with age and revealed female preponderance, geographic diversity, and disparity with regard to anatomic site. OA of the knee contributed the most to the overall burden, while OA of the hip had the highest EAPC in most regions. OA has remained a major public health concern worldwide over the past decades. The prevalence of OA has increased and diversified by geographic location and affected joint. Prevention and early treatment are pivotal to mitigating the growing burden of OA.
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发表时间: 2019-11-01
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