Neural Mechanisms of Sustained Attention Are Rhythmic.
Neural Mechanisms of Sustained Attention Are Rhythmic.
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DOI：
10.1016/j.neuron.2018.07.032
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发表时间：
2018-08-22
期刊：
影响因子：
16.2
通讯作者：
Kastner S
中科院分区：
文献类型：
--
作者：
Helfrich RF;Fiebelkorn IC;Szczepanski SM;Lin JJ;Parvizi J;Knight RT;Kastner S
注意力的经典模型表明，持续的神经放电构成了持续注意力的神经相关性。然而，最近的证据表明，行为表现随着时间的推移而波动，表现出与持续的振荡大脑活动的光谱特征非常相似的时间动态。因此，有人提出周期性神经元兴奋性波动可能会影响注意力分配和外在行为。然而，支持这一观点的经验证据很少。在这里，我们通过检查大规模硬膜下记录的数据来解决这个问题，使用两种不同的注意力任务来跟踪高时间分辨率的感知能力。我们的结果表明，即使在持续空间注意力的状态下，知觉结果也会随着θ相位的变化而变化。这些效应在单个受试者水平上很强大，表明有节奏的知觉采样是额顶叶注意力网络的固有属性。总的来说，这些发现支持了这样的观点：自上而下注意力的功能架构本质上是有节奏的。赫尔弗里希等人。证明持续注意力的神经基础是有节奏的。他们利用人类颅内记录表明，注意力分配和外在行为是由约 4 Hz 的θ节律调节的，该节律可预测内源性兴奋性波动。
Classic models of attention suggest that sustained neural firing constitutes a neural correlate of sustained attention. However, recent evidence indicates that behavioral performance fluctuates over time, exhibiting temporal dynamics that closely resemble the spectral features of ongoing, oscillatory brain activity. Therefore, it has been proposed that periodic neuronal excitability fluctuations might shape attentional allocation and overt behavior. However, empirical evidence to support this notion is sparse. Here, we address this issue by examining data from large-scale subdural recordings, using two different attention tasks that track perceptual ability at high temporal resolution. Our results reveal that perceptual outcome varies as a function of the theta phase even in states of sustained spatial attention. These effects were robust at the single-subject level, suggesting that rhythmic perceptual sampling is an inherent property of the frontoparietal attention network. Collectively, these findings support the notion that the functional architecture of top-down attention is intrinsically rhythmic. Helfrich et al. demonstrate that the neural basis of sustained attention is rhythmic. Using human intracranial recordings, they show that attentional allocation and overt behavior are modulated by a ~4 Hz theta rhythm that predicts endogenous excitability fluctuations.
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DOI：
10.1073/pnas.1414491112
发表时间：
2015-03-03
影响因子：
11.1
作者：
Flinker, Adeen;Korzeniewska, Anna;Crone, Nathan E.
通讯作者：
Crone, Nathan E.
影响因子：
5.3
作者：
Busch, Niko A.;Dubois, Julien;VanRullen, Rufin
通讯作者：
VanRullen, Rufin
额叶网络中的动态相互作用是有节奏的空间关注的基础。
影响因子：
16.2
作者：
Fiebelkorn IC;Pinsk MA;Kastner S
通讯作者：
Kastner S
影响因子：
5.7
作者：
Dale, AM;Fischl, B;Sereno, MI
通讯作者：
Sereno, MI
影响因子：
4.1
作者：
EGLY, R;DRIVER, J;RAFAL, RD
通讯作者：
RAFAL, RD