Neurocysticercosis: a review.
Neurocysticercosis: a review.
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DOI：
10.1100/2012/159821
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发表时间：
2012
影响因子：
--
通讯作者：
Del Brutto OH
中科院分区：
文献类型：
--
作者：
Del Brutto OH
脑囊虫病是神经系统最常见的寄生虫感染，也是全球获得性癫痫的主要原因。这种疾病发生时，人类通过从受污染的食物中摄取虫卵成为猪带绦虫的中间宿主，或者最常见的情况是，通过粪便到口腔的途径直接从带绦虫的人那里摄取虫卵。囊虫可能位于脑实质、蛛网膜下腔、脑室系统或脊髓，引起的病理改变与脑囊虫病的多形性有关。癫痫是最常见的临床表现，但许多患者表现为局灶性功能障碍、颅内高压或认知能力下降。在结合神经影像研究和免疫学测试结果解释临床数据后，准确诊断脑囊虫病是可能的。杀囊药物的引入改变了大多数脑囊虫病患者的预后。这些药物已被证明可以减轻脑部感染的负担，并改善大多数患者的临床病程。应采取进一步措施，通过实施防治措施来根除该病，控制措施包括针对成虫携带者、受感染的猪和环境中的虫卵等生命周期中所有相互关联的步骤进行控制。
Neuroysticercosis is the most common helminthic infection of the nervous system, and a leading cause of acquired epilepsy worldwide. The disease occurs when humans become intermediate hosts of Taenia solium by ingesting its eggs from contaminated food or, most often, directly from a taenia carrier by the fecal-to-oral route. Cysticerci may be located in brain parenchyma, subarachnoid space, ventricular system, or spinal cord, causing pathological changes that are responsible for the pleomorphism of neurocysticercosis. Seizures are the most common clinical manifestation, but many patients present with focal deficits, intracranial hypertension, or cognitive decline. Accurate diagnosis of neurocysticercosis is possible after interpretation of clinical data together with findings of neuroimaging studies and results of immunological tests. The introduction of cysticidal drugs have changed the prognosis of most patients with neurocysticercosis. These drugs have shown to reduce the burden of infection in the brain and to improve the clinical course of the disease in most patients. Further efforts should be directed to eradicate the disease through the implementation of control programs against all the interrelated steps in the life cycle of T. solium, including human carriers of the adult tapeworm, infected pigs, and eggs in the environment.
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影响因子：
9.9
作者：
DELBRUTTO, OH
通讯作者：
DELBRUTTO, OH
影响因子：
5.6
作者：
Del Brutto, OH;Santibáñez, R;García, HH
通讯作者：
García, HH
影响因子：
9.9
作者：
DELBRUTTO, OH;SANTIBANEZ, R;ALARCON, TA
通讯作者：
ALARCON, TA
影响因子：
9.9
作者：
Garcia, HH;Gilman, RH;Rocca, U
通讯作者：
Rocca, U
影响因子：
11
作者：
DelBrutto, OH
通讯作者：
DelBrutto, OH