Pore formation in lipid bilayer membranes made of phosphatidylcholine and cholesterol followed by means of constant current.

Pore formation in lipid bilayer membranes made of phosphatidylcholine and cholesterol followed by means of constant current.
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DOI:
10.1007/s12013-012-9459-6
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发表时间:
2013-05
影响因子:
2.6
通讯作者:
Figaszewski, Zbigniew Artur
Figaszewski, Zbigniew Artur
中科院分区:
生物学4区
文献类型:
--
作者:
Naumowicz, Monika;Figaszewski, Zbigniew Artur

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本文介绍了计时电位法在脂双层研究中的应用。实验在由磷脂酰胆碱和胆固醇组成的双层脂质膜上进行,并使用涂敷技术形成。计时电位法(U = f(t))测量用于确定膜电容、电阻和击穿电压以及孔电导和直径。
This paper describes the application of chronopotentiometry to lipid bilayer research. The experiments were performed on bilayer lipid membranes composed of phosphatidylcholine and cholesterol and formed using the painting technique. Chronopotentiometric (U = f(t)) measurements were used to determine the membrane capacitance, resistance, and breakdown voltage as well as pore conductance and diameter.
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