Long-term survival of young women receiving fertility-sparing surgery for ovarian cancer in comparison with those undergoing radical surgery.
Long-term survival of young women receiving fertility-sparing surgery for ovarian cancer in comparison with those undergoing radical surgery.
复制标题
与接受根治性手术的年轻女性接受卵巢癌的长期生存。
DOI：
10.1038/bjc.2011.394
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发表时间：
2011-10-25
影响因子：
8.8
通讯作者：
Kikkawa, F.
中科院分区：
文献类型：
--
作者：
Kajiyama, H.;Shibata, K.;Mizuno, M.;Umezu, T.;Suzuki, S.;Nawa, A.;Kawai, M.;Nagasaka, T.;Kikkawa, F.
比较接受保留生育手术 (FSS) 和接受根治性手术 (RS) 的 I 期上皮性卵巢癌 (EOC) 患者的临床结果。经过中央病理审查和多机构病历检索，共对572例患者进行了回顾性评估。所有患者被分为三组：A组{FSS(n=74)；年龄，⩽40} B 组和 C 组 [RS;年龄，40⩾{(B)，n=52} 40<{(C)，n=446}]。各组患者的五年总生存率（OS）和无病生存率（DFS）如下：A组90.8%（OS）/87.9%（DFS）； B组，88.3%（OS）/84.4%（DFS）； C 组，分别为 90.6%（OS）/85.3%（DFS）（OS，P=0.802；DFS，P=0.765）。此外，IA或IC期三组的OS和DFS没有显着差异（分别为OS（IA），P=0.387；DFS（IA），P=0.314；OS（IC），P=0.993；DFS（IC），P=0.990）。此外，FSS 组中 1-2 级或 3 级肿瘤患者的预后并不比 RS 组中的患者更差。与接受 RS 治疗的患者相比，接受 FSS 治疗的 I 期 EOC 患者预后良好。
To compare the clinical outcome of patients with stage I epithelial ovarian cancer (EOC) who received with fertility-sparing surgery (FSS) with those who underwent radical surgery (RS). After a central pathological review and search of the medical records from multiple institutions, a total of 572 patients were retrospectively evaluated. All patients were divided into three groups: group A {FSS (n=74); age, ⩽40} groups B and C [RS; age, 40⩾{(B), n=52} 40<{(C), n=446}]. Five-year overall survival (OS) and disease-free survival (DFS) rates of patients in the groups were as follows: group A, 90.8% (OS)/87.9% (DFS); group B, 88.3% (OS)/84.4% (DFS); group C, 90.6% (OS)/85.3% (DFS), respectively (OS, P=0.802; DFS, P=0.765). Additionally, there was no significant difference in OS and DFS among the three groups stratified to stage IA or IC (OS (IA), P=0.387; DFS (IA), P=0.314; OS (IC), P=0.993; DFS (IC), P=0.990, respectively). Furthermore, patients with a grade 1–2 or 3 tumours in the FSS group did not have a poorer prognosis than those in the RS group. Stage I EOC patients treated with FSS showed an acceptable prognosis compared with those who underwent RS.
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影响因子：
3.8
作者：
Kajiyama, H.;Shibata, K.;Kikkawa, F.
通讯作者：
Kikkawa, F.
影响因子：
4.7
作者：
Schilder, JM;Thompson, AM;van Nagell, J
通讯作者：
van Nagell, J
影响因子：
4.7
作者：
Kajiyama, Hiroaki;Shibata, Kiyosumi;Kikkawa, Fumitaka
通讯作者：
Kikkawa, Fumitaka
DOI：
10.1046/j.1525-1438.1993.03020072.x
发表时间：
1993-03-01
影响因子：
4.8
作者：
BERTELSEN, K;HOLUND, B;ANDERSEN, E
通讯作者：
ANDERSEN, E
DOI：
10.1111/j.1471-0528.1985.tb03056.x
发表时间：
1985-01-01
期刊：
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
影响因子：
--
作者：
SMEDLEY, H;SIKORA, K
通讯作者：
SIKORA, K