The 2000 tularemia outbreak: a case-control study of risk factors in disease-endemic and emergent areas, Sweden.

The 2000 tularemia outbreak: a case-control study of risk factors in disease-endemic and emergent areas, Sweden.
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DOI:
10.3201/eid0809.020051
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发表时间:
2002-09
影响因子:
11.8
通讯作者:
Tegnell A
Tegnell A
中科院分区:
医学2区
文献类型:
--
作者:
Eliasson H;Lindbäck J;Nuorti JP;Arneborn M;Giesecke J;Tegnell A

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在一项病例对照研究中,对2000年瑞典大范围爆发的图拉热症进行了调查,其中270例报告的图拉热症病例与438例对照进行了比较。疫情影响了迄今为止罕见的图拉热病的瑞典部分地区,并将这些“紧急”地区与疾病流行地区进行了比较。多因素回归分析显示蚊虫叮咬是主要危险因素,优势比(OR)为8.8。其他危险因素包括养猫(OR 2.5)和干农活(OR 3.2)。只有在疾病流行地区,农业才是一个危险因素。淋巴结肿大和伤口感染在急诊区域更常见,而肺炎在疾病流行区域更常见。蚊子叮咬似乎在图拉热症的传播中起着重要作用。猫的所有权与疾病之间的联系值得进一步研究。
A widespread outbreak of tularemia in Sweden in 2000 was investigated in a case-control study in which 270 reported cases of tularemia were compared with 438 controls. The outbreak affected parts of Sweden where tularemia had hitherto been rare, and these “emergent” areas were compared with the disease-endemic areas. Multivariate regression analysis showed mosquito bites to be the main risk factor, with an odds ratio (OR) of 8.8. Other risk factors were owning a cat (OR 2.5) and farm work (OR 3.2). Farming was a risk factor only in the disease-endemic area. Swollen lymph nodes and wound infections were more common in the emergent area, while pneumonia was more common in the disease-endemic area. Mosquito bites appear to be important in transmission of tularemia. The association between cat ownership and disease merits further investigation.
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