Parental childhood growth and offspring birthweight: pooled analyses from four birth cohorts in low and middle income countries.
Parental childhood growth and offspring birthweight: pooled analyses from four birth cohorts in low and middle income countries.
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父母儿童期的增长和后代的出生体重：低收入国家和中等收入国家的四个出生队列的汇总分析。
DOI：
10.1002/ajhb.22614
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发表时间：
2015-01
影响因子：
2.9
通讯作者：
Martorell, R.
中科院分区：
文献类型：
--
作者：
Addo, O. Y.;Stein, A. D.;Fall, C. H. D.;Gigante, D. P.;Guntupalli, A. M.;Horta, B. L.;Kuzawa, C. W.;Lee, N.;Norris, S. A.;Osmond, C.;Prabhakaran, P.;Richter, L. M.;Sachdev, H. P. S.;Martorell, R.
父母和后代出生时的大小之间的关联已经建立，但父母在不同年龄的增长作为后代出生体重的预测因素的相对重要性还不太确定。在这里，我们模拟父母的出生体重和出生后的条件生长在特定的年龄段作为后代出生体重的预测。我们分析了来自3，392名参与四个前瞻性出生队列的成年人及其5，506名后代的数据。研究中心或后代性别之间无显著异质性。母亲出生体重增加1 SD与后代出生体重增加102 g相关，母亲0-2岁身长增长1 SD与46 g相关，母亲儿童中期（MC）-成年身高增长1 SD与27 g相关。母体相对体重测量与24 g后代出生体重增加（2岁- MC）和49 g MC-成年期相关，但与0-2岁早期相对体重无关。对于父亲，出生体重和线性/长度增长从0-2年分别与后代出生体重增加57和56克，但此后没有。母亲和父亲的出生体重和从出生到2岁的生长预测后代的出生体重。母体生长从MC-成年，相对重量从2-MC和MC-成年也预测后代出生体重。这些发现表明，父母双方在生命早期共享基因和/或充足的营养可能会给下一代带来好处，并强调了怀孕前母亲身高和体重的重要性。母系比父系与后代出生体重的关系更强，这与改善年轻女性的早期生长条件可以改善下一代出生结果的假设一致。Am. J.哈姆。27：99-105，2015.© 2014 The Authors American Journal of Human Biology由Wiley Periodicals，Inc.出版
Associations between parental and offspring size at birth are well established, but the relative importance of parental growth at different ages as predictors of offspring birthweight is less certain. Here we model parental birthweight and postnatal conditional growth in specific age periods as predictors of offspring birthweight. We analyzed data from 3,392 adults participating in four prospective birth cohorts and 5,506 of their offspring. There was no significant heterogeneity by study site or offspring sex. 1SD increase in maternal birthweight was associated with offspring birthweight increases of 102 g, 1SD in maternal length growth 0–2 year with 46 g, and 1SD in maternal height growth Mid-childhood (MC)-adulthood with 27 g. Maternal relative weight measures were associated with 24 g offspring birth weight increases (2 year- MC) and 49 g for MC-adulthood period but not with earlier relative weight 0–2 year. For fathers, birthweight, and linear/length growth from 0–2 year were associated with increases of 57 and 56 g in offspring birthweight, respectively but not thereafter. Maternal and paternal birthweight and growth from birth to 2 year each predict offspring birthweight. Maternal growth from MC-adulthood, relative weight from 2-MC and MC-adulthood also predict offspring birthweight. These findings suggest that shared genes and/or adequate nutrition during early life for both parents may confer benefits to the next generation, and highlight the importance of maternal height and weight prior to conception. The stronger matrilineal than patrilineal relationships with offspring birth weight are consistent with the hypothesis that improving the early growth conditions of young females can improve birth outcomes in the next generation. Am. J. Hum. Biol. 27:99–105, 2015. © 2014 The Authors American Journal of Human Biology Published by Wiley Periodicals, Inc.
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影响因子：
2.9
作者：
Chung, Green C.;Kuzawa, Christopher W.
通讯作者：
Kuzawa, Christopher W.
影响因子：
6.1
作者：
Ibáñez, L;Potau, N;de Zegher, F
通讯作者：
de Zegher, F
影响因子：
7.7
作者：
Horta BL;Gigante DP;Osmond C;Barros FC;Victora CG
通讯作者：
Victora CG
影响因子：
168.9
作者：
Adair, Linda S.;Fall, Caroline H. D.;Osmond, Clive;Stein, Aryeh D.;Martorell, Reynaldo;Ramirez-Zea, Manuel;Sachdev, Harshpal Singh;Dahly, Darren L.;Bas, Isabelita;Norris, Shane A.;Micklesfield, Lisa;Hallal, Pedro;Victora, Cesar G.
通讯作者：
Victora, Cesar G.
影响因子：
7.7
作者：
Richter, Linda;Norris, Shane;Cameron, Noel
通讯作者：
Cameron, Noel