Mindfulness training for coping with hot flashes: results of a randomized trial.
Mindfulness training for coping with hot flashes: results of a randomized trial.
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DOI：
10.1097/gme.0b013e318204a05c
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发表时间：
2011-06
期刊：
影响因子：
--
通讯作者：
Olendzki N
中科院分区：
文献类型：
--
作者：
Carmody JF;Crawford S;Salmoirago-Blotcher E;Leung K;Churchill L;Olendzki N
研究参加专注力训练项目（专注力减压）对潮热和盗汗困扰程度的影响。随机试验纳入110名绝经晚期和绝经早期妇女，平均每天出现≥5次中度或重度潮热（包括盗汗）。采用等候名单对照，干预后随访3个月。主要观察指标为前24小时内潮热和盗汗的困扰程度。次要指标：潮热强度、生活质量、失眠、焦虑、感知压力。基线平均潮热频率为7.87次(SD 3.44) /天，盗汗2.81次(SD 1.76)/天。平均烦恼评分为3.18 (SD 0.55)（“中度烦恼/极度烦恼”）。所有的分析都是为了治疗，并控制基线值。女性体内潮热引起的焦虑变化在治疗组之间差异显著（周与治疗组相互作用P=0.042）。干预结束时，正念减压组的困扰平均下降14.77%，而WLC组平均下降6.79%。在20周时，MBSR的总麻烦减少率为21.62%，WLC的总麻烦减少率为10.50%。治疗组间经基线调整后的热闪强度变化无差异（周×治疗组相互作用P=0.692）。正念减压组在生活质量（P=0.022）、主观睡眠质量（P= 0.009）、焦虑（P=0.005）和感知压力（P=0.001）方面有临床意义的改善。干预后3个月仍保持改善。我们的数据表明，正念减压可能是一种临床上重要的资源，可以减少女性因潮热和盗汗而经历的烦恼和痛苦程度。
Study the effect of participation in a mindfulness training program (Mindfulness Based Stress Reduction) on degree of bother from hot flashes and night sweats. Randomized trial of 110 late perimenopausal and early post-menopausal women experiencing average of ≥5 moderate or severe hot flashes (including night sweats)/day. A wait list control was used, with three-month post-intervention follow-up. Main outcome was degree of bother from hot flashes and night sweats in previous 24 hours. Secondary measures: hot flash intensity, quality of life, insomnia, anxiety, perceived stress. Baseline average hot flash frequency was 7.87 (SD 3.44) and 2.81 night sweats (SD 1.76)/day. Mean bothersomeness score was 3.18 (SD 0.55) (‘moderately bothered/extremely bothered’). All analyses were intent to treat, and controlled for baseline values. Within-woman changes in bother from hot flashes differed significantly by treatment arm (week × treatment arm interaction P=0.042). At completion of intervention, bother in the MBSR arm decreased on average by 14.77% versus 6.79% for WLC. At 20 weeks total reduction in bother for MBSR was 21.62% and 10.50% for WLC. Baseline-adjusted changes in hot flash intensity did not differ between treatment arms (week × treatment arm interaction P=0.692). The MBSR arm made clinically significant improvements in quality of life (P=0.022), subjective sleep quality (p=0.009), anxiety (P=0.005), and perceived stress (P=0.001). Improvements were maintained 3 months post-intervention. Our data suggest that MBSR may be a clinically significant resource in reducing the degree of bother and distress women experience from hot flashes and night sweats.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
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影响因子：
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作者：
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DOI：
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发表时间：
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作者：
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影响因子：
7.2
作者：
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通讯作者：
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