Effects of Dietary Tributyrin on Growth Performance, Biochemical Indices, and Intestinal Microbiota of Yellow-Feathered Broilers.
Effects of Dietary Tributyrin on Growth Performance, Biochemical Indices, and Intestinal Microbiota of Yellow-Feathered Broilers.
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DOI：
10.3390/ani11123425
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发表时间：
2021-12-01
期刊：
影响因子：
--
通讯作者：
Zhang H
中科院分区：
文献类型：
--
作者：
Gong L;Xiao G;Zheng L;Yan X;Qi Q;Zhu C;Feng X;Huang W;Zhang H
由于抗生素残留和抗生素耐药性等不良问题，家禽生产中的各种抗生素产品正逐渐在世界范围内被禁止。三丁酸甘油酯是抗生素的潜在替代品。本研究结果表明，三丁酸甘油酯可以通过调节血液生化指标和盲肠菌群组成来改善黄羽肉鸡的生长性能。据我们所知，很少有研究调查了三丁酸甘油酯对肉鸡肠道微生物群的影响及其与生长性能的关系。这将为后抗生素时代的三丁酸甘油酯在畜牧业中的应用提供科学依据。本试验旨在研究三丁酸甘油酯对黄羽肉鸡生长性能、生化指标和肠道菌群的影响。选取360只1日龄雏鸡，随机分为正常对照组（NC）、抗生素组（PC）和三丁酸甘油酯（250 mg/kg）组（TB） 3个处理，每个处理6个重复，每重复20只鸡，试验期63 d。结果表明：与对照组相比，TB组肉鸡在第22 ~ 42天的饲料系数（FCR）降低（p < 0.05），肉鸡末重和FCR总体上有升高和降低的趋势。TB组全期肌酸浓度最高（p < 0.05）。结核治疗增加了拟杆菌门的相对丰度，降低了厚壁菌门的相对丰度。主坐标分析得出了三个组的清晰聚类。线性判别分析效应大小分析发现结核类群中有7个差异丰富的类群，包括拟杆菌门的几个成员。三丁酸甘油酯处理肉鸡艾森伯格菌、Phascolarctobacterium、Megasphaera和肠子单胞菌的相对丰度增加。Spearman相关分析发现，艾森伯格菌丰度与整体饲料效率存在相关性。由此可见，三丁酸甘油酯可以通过调节肉鸡血液生化指标和盲肠菌群组成来改善肉鸡的生长性能。
Various antibiotic products in poultry production are gradually being banned around the world due to the adverse problems including the antibiotic residues and antibiotic resistance. Tributyrin was a potential alternative to antibiotics. The results of the present study indicated that tributyrin could improve the growth performance by modulating blood biochemical indices and the cecal microflora composition of yellow-feathered broilers. To the best of our knowledge, few studies investigated the effects of tributyrin on intestinal microbiota and its relationship with growth performance in broilers. This will provide a scientific basis for the application of tributyrin in animal husbandry in this post-antibiotic era. This study aimed to evaluate the effects of tributyrin on growth performance, biochemical indices and intestinal microbiota of yellow-feathered broilers. 360 one-day-old chicks were randomly allocated to three treatments with six replicates of 20 chicks each, including a normal control group (NC), an antibiotic group (PC), and a tributyrin (250 mg/kg) group (TB) for 63 days. The results showed that compared with the control, the feed conversion ratio (FCR) in the TB group decreased during the d22 to d42 (p < 0.05) and overall, the final weight and FCR of broilers tended to increase and decrease, respectively. Moreover, the TB group showed the highest creatine concentrations at the entire period (p < 0.05). TB treatment increased the Bacteroidetes relative abundance and decreased Firmicutes. Principal coordinates analysis yielded clear clustering of the three groups. Linear discriminant analysis effect size analysis found seven differentially abundant taxa in the TB group, including several members of Bacteroidedetes. The relative abundance of Eisenbergiella, Phascolarctobacterium, Megasphaera and Intestinimonas increased in tributyrin-treated broilers. Spearman correlation analysis identified a correlation between Eisenbergiella abundance and overall feed efficiency. These results demonstrated that tributyrin could improve the growth performance by modulating blood biochemical indices and the cecal microflora composition of broilers.
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影响因子：
3.2
作者：
Cho, KH;Cho, D;Salyers, AA
通讯作者：
Salyers, AA
影响因子：
3.7
作者：
He J;Dong L;Xu W;Bai K;Lu C;Wu Y;Huang Q;Zhang L;Wang T
通讯作者：
Wang T
细粒棘球绦虫感染导致小鼠肠道内艾森氏菌属和副杆菌属增加
影响因子：
5.2
作者：
Bao, Jianling;Zheng, Huajun;McManus, Donald P.
通讯作者：
McManus, Donald P.
DOI：
10.1016/b978-0-12-815249-2.00044-0
发表时间：
2019-01-01
期刊：
MICROBIOME AND METABOLOME IN DIAGNOSIS, THERAPY, AND OTHER STRATEGIC APPLICATIONS
影响因子：
--
作者：
Dahiya, Dinesh Kumar;Renuka;Shukla, Pratyoosh
通讯作者：
Shukla, Pratyoosh
影响因子：
4.4
作者：
Onrust, Lonneke;Baeyen, Steve;Van Immerseel, Filip
通讯作者：
Van Immerseel, Filip