Sleep modulates word-pair learning but not motor sequence learning in healthy older adults.
Sleep modulates word-pair learning but not motor sequence learning in healthy older adults.
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DOI：
10.1016/j.neurobiolaging.2011.06.029
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发表时间：
2012-05
影响因子：
4.2
通讯作者：
Spencer RM
中科院分区：
文献类型：
--
作者：
Wilson JK;Baran B;Pace-Schott EF;Ivry RB;Spencer RM
睡眠对年轻人的记忆力有很大的帮助。然而，我们对健康老年人睡眠对记忆的影响知之甚少。我们使用两项任务，一项分析运动技能学习，另一项分析非运动/陈述性学习，来检查无睡眠障碍的年轻人（20-34岁）、中年人（35-50岁）和老年人（51-70岁）在离线状态下的表现变化。在早上或晚上进行的初始阶段，参与者学习了一个动作序列和一组单词对。训练后12小时和24小时分别进行了两次记忆测试，让我们分析休息（包括睡眠或正常清醒）后的离线巩固情况。老年人在运动序列学习任务中的睡眠依赖性表现变化减少。相比之下，在单词配对学习任务中，三个年龄组的睡眠依赖表现变化相似。与年龄相关的睡眠变化或编码或睡眠期间激活的网络可能导致与年龄相关的运动序列巩固下降。有趣的是，这些变化并不影响陈述性记忆。
Sleep benefits memory across a range of tasks for young adults. However, remarkably little is known of the role of sleep on memory for healthy older adults. We used two tasks, one assaying motor skill learning and the other assaying non-motor/declarative learning, to examine off-line changes in performance in young (20–34 yrs), middle-aged (35–50 yrs), and older (51–70 yrs) adults without disordered sleep. During an initial session, conducted either in the morning or evening, participants learned a motor sequence and a list of word pairs. Memory tests were given twice, 12 and 24 hours after training, allowing us to analyze off-line consolidation after a break that included sleep or normal wake. Sleep dependent performance changes were reduced in older adults on the motor sequence learning task. In contrast, sleep dependent performance changes were similar for all three age groups on the word pair learning task. Age-related changes in sleep or networks activated during encoding or during sleep may contribute to age-related declines in motor sequence consolidation. Interestingly, these changes do not affect declarative memory.
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DOI：
10.1891/1945-8959.10.2.167
发表时间：
2011-06-01
期刊：
Journal of cognitive education and psychology : JCEP
影响因子：
--
作者：
Donohue KC;Spencer RM
通讯作者：
Spencer RM
影响因子：
5.3
作者：
Brown, Rachel M.;Robertson, Edwin M.
通讯作者：
Robertson, Edwin M.
影响因子：
3.7
作者：
Ellenbogen, Jeffrey M.;Hulbert, Justin C.;Stickgold, Robert
通讯作者：
Stickgold, Robert
影响因子：
2.1
作者：
Aly, Mariam;Moscovitch, Morris
通讯作者：
Moscovitch, Morris
影响因子：
5.6
作者：
Ohayon, MM;Carskadon, MA;Vitiello, MV
通讯作者：
Vitiello, MV