The Warburg effect: Saturation of mitochondrial NADH shuttles triggers aerobic lactate fermentation.
The Warburg effect: Saturation of mitochondrial NADH shuttles triggers aerobic lactate fermentation.
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DOI:
10.1016/j.molcel.2022.08.004
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发表时间:
2022-09-01
期刊:
影响因子:
16
通讯作者:
Lunt, Sophia Y.
中科院分区:
文献类型:
--
作者:
Medeiros, Hyllana C. D.;Lunt, Sophia Y.
In this issue of Molecular Cell, Wang et al. investigate the Warburg effect in proliferating cells and demonstrate that lactate fermentation is a secondary mechanism activated after mitochondrial shuttles exceed their capacity to oxidize cytosolic NADH.
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