Trabecular bone scales allometrically in mammals and birds.

Trabecular bone scales allometrically in mammals and birds.
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DOI:
10.1098/rspb.2011.0069
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发表时间:
2011-10-22
期刊:
Proceedings. Biological sciences
影响因子:
--
通讯作者:
Shefelbine SJ
Shefelbine SJ
中科院分区:
其他
文献类型:
--
作者:
Doube M;Klosowski MM;Wiktorowicz-Conroy AM;Hutchinson JR;Shefelbine SJ

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许多骨骼在内部由小梁网状结构支撑。全骨长度和直径的伸缩已经被广泛研究,但小梁网络的伸缩还没有很好的特征。我们分析了90种陆生哺乳动物和鸟类股骨的骨小梁几何结构,这些物种的体重从3克到3400公斤不等。我们发现,骨体积分数并不随动物大小而大幅增加,而较大动物股骨中的骨小梁比较小动物的骨小梁更厚、距离更远,单位体积更小。有限元模拟表明,在等载荷作用下,骨小梁的伸缩不会改变骨小梁的整体硬度,但会改变骨小梁内的应变。骨小梁组织的异速生长可能有助于骨骼承受负荷的能力,而不会招致增加骨量的生理或机械成本。
Many bones are supported internally by a latticework of trabeculae. Scaling of whole bone length and diameter has been extensively investigated, but scaling of the trabecular network is not well characterised. We analysed trabecular geometry in the femora of 90 terrestrial mammalian and avian species with body masses ranging from 3 g to 3400 kg. We found that bone volume fraction does not scale substantially with animal size, while trabeculae in larger animals’ femora are thicker, further apart and fewer per unit volume than in smaller animals. Finite element modelling indicates that trabecular scaling does not alter the bulk stiffness of trabecular bone, but does alter strain within trabeculae under equal applied loads. Allometry of bone’s trabecular tissue may contribute to the skeleton’s ability to withstand load, without incurring the physiologic or mechanical costs of increasing bone mass.
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