Newborn cortical neurons: only for neonates?
Newborn cortical neurons: only for neonates?
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新生儿皮质神经元:仅适用于新生儿?
DOI:
10.1016/j.tins.2012.09.004
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发表时间:
2013-01
影响因子:
15.9
通讯作者:
Bordey A
中科院分区:
文献类型:
--
作者:
Feliciano DM;Bordey A
Despite a century of debate over the existence of adult cortical neurogenesis, a consensus has not yet been reached. Here, we review evidence of the existence, origin, migration, and integration of neurons into the adult and neonatal cerebral cortex. We find that the lack of consensus likely stems from the low rate of postnatal cortical neurogenesis that has been observed, the fact that it may be limited to sub-types of interneurons, and variability in other conditions, both physiological and environmental. We emphasize that neurogenesis occurs in the neonatal cortex and neural stem cells exist into adulthood; perhaps these progenitors are dormant, but they may be reactivated, for example, with injury.
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通讯作者:
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