Chronic alcoholism and the frontal lobe: which executive functions are imparied?
Chronic alcoholism and the frontal lobe: which executive functions are imparied?
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慢性酒精中毒和额叶：哪些执行功能受到损害？
DOI：
10.1034/j.1600-0404.2002.0o315.x
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发表时间：
2002
影响因子：
3.5
通讯作者：
D. Soragna
中科院分区：
文献类型：
--
作者：
M. T. Ratti;P. Bo;A. Giardini;D. Soragna
目的-在过去的十年中，各种假说已经提出了关于慢性酒精中毒影响的认知功能。本研究的目的是确定慢性酒精中毒的执行功能障碍的模式，阐明与额叶相关的特定功能之间可能存在的差异。方法：22名男性酗酒者和22名对照者，年龄，教育水平和智商相匹配，参加了这项研究。采用MMPI和一系列神经心理学测试[即数字符号、连线测验、Stroop测验、数字划消测验、威斯康星州卡片分类测验（WCST）、简单反应时和选择反应时]评估额叶功能。结果-酗酒者被发现在广泛的执行域受损，与Stroop测试，但显示出的趋势，患者和对照组之间的统计学显着差异。结论-除了侵略-我们的主题没有高侵略量表得分-“额叶假说”，根据酒精中毒患者受损的功能测试相关的额叶，因此在我们的样本中得到证实。
Objective– Over the last decade, various hypotheses have been advanced concerning the cognitive functions affected by chronic alcoholism. The aim of this study was to identify the pattern of executive function impairment in chronic alcoholism, shedding light on possible differences between specific functions related to the frontal lobe. Methods– Twenty‐two male alcoholics and 22 controls, matched for age, educational level and IQ, were enrolled in the study. MMPI and a battery of neuropsychological tests [i.e. digit symbol, trail making test, Stroop test, digit cancellation test, Wisconsin card sorting test (WCST), simple and choice reaction times] for assessing frontal lobe functioning were administered. Results– The alcoholics were found to be impaired in a wide range of executive domains, with the exception of the Stroop test, which nevertheless showed a trend towards statistically significant differences between patients and controls. Conclusion– With the exception of aggression – our subjects did not have high aggression scale scores – the `frontal lobe hypothesis', according to which alcoholic patients are impaired on function tests related to the frontal lobe, was therefore confirmed in our sample.
酒精康复计划居民的神经心理功能和心理社会状态。
影响因子：
4.4
作者：
Zlotnick,C;Agnew,J
通讯作者：
Agnew,J
酗酒者的神经心理学测量和事件相关电位：相互关系、长期可靠性和恢复饮酒的预测。
影响因子：
3
作者：
Parsons,OA
通讯作者：
Parsons,OA