Structure and steroidogenesis of the placenta in the Antarctic minke whale (Balaenoptera bonaerensis).
Structure and steroidogenesis of the placenta in the Antarctic minke whale (Balaenoptera bonaerensis).
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DOI：
10.1262/jrd.2012-132
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Kitamura N
中科院分区：
文献类型：
--
作者：
Sasaki M;Amano Y;Hayakawa D;Tsubota T;Ishikawa H;Mogoe T;Ohsumi S;Tetsuka M;Miyamoto A;Fukui Y;Budipitojo T;Kitamura N
描述鲸鱼胎盘的结构和功能随妊娠进展的报道很少。因此，在本研究中，对南极小须鲸的胎盘和非妊娠子宫进行了形态学和免疫组织化学观察。胎盘和非妊娠子宫是从日本东京鲸类研究所组织的第 15、16 和 18 届日本南极特别许可鲸鱼研究计划 (JARPA) 和第一届 JARPA II 中收集的。从宏观和微观观察，南极小须鲸的胎盘是弥漫性上皮绒毛胎盘。绒毛膜通过初级、次级和三级绒毛与子宫内膜交错，其中不含有双核细胞等特化的滋养层细胞，并且随着妊娠的进展，交错变得复杂。此外，随着胎儿的生长，胎儿和母体的血管分别深入滋养层细胞和子宫内膜上皮。小须鲸胎盘呈褶皱状，而不是手指状。在非妊娠和妊娠子宫中，分布有许多子宫腺体。妊娠子宫内膜浅层的子宫腺体较深层的子宫腺体管腔较宽，上皮细胞较大。另一方面，在非妊娠子宫内膜中，子宫腺体的管腔比妊娠子宫内膜更窄，上皮细胞也更小。在免疫组织化学检测中，在大多数滋养层细胞中检测到 P450scc 的免疫反应性，但在非妊娠子宫中未检测到，这表明滋养层上皮细胞合成并分泌性类固醇激素和/或其前体以维持南极小须鲸的妊娠。
There are few reports describing the structure and function of the whale placenta with the advance of pregnancy. In this study, therefore, the placenta and nonpregnant uterus of the Antarctic minke whale were observed morphologically and immunohistochemically. Placentas and nonpregnant uteri were collected from the 15th, 16th and 18th Japanese Whale Research Programme with Special Permit in the Antarctic (JARPA) and 1st JARPA II organized by the Institute of Cetacean Research in Tokyo, Japan. In the macro- and microscopic observations, the placenta of the Antarctic minke whale was a diffuse and epitheliochorial placenta. The chorion was interdigitated to the endometrium by primary, secondary and tertiary villi, which contained no specialized trophoblast cells such as binucleate cells, and the interdigitation became complicated with the progress of gestation. Furthermore, fetal and maternal blood vessels indented deeply into the trophoblast cells and endometrial epithelium respectively with fetal growth. The minke whale placenta showed a fold-like shape as opposed to a finger-like shape. In both nonpregnant and pregnant uteri, many uterine glands were distributed. The uterine glands in the superficial layer of the pregnant endometrium had a wide lumen and large epithelial cells as compared with those in the deep layer. On the other hand, in the nonpregnant endometrium, the uterine glands had a narrower lumen and smaller epithelial cells than in the pregnant endometrium. In immunohistochemical detection, immunoreactivity for P450scc was detected in most trophoblast cells, but not in nonpregnant uteri, suggesting that trophoblast epithelial cells synthesized and secreted the sex steroid hormones and/or their precursors to maintain the pregnancy in the Antarctic minke whale.
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影响因子：
2.8
作者：
Asada, M;Tetsuka, M;Fukui, Y
通讯作者：
Fukui, Y
DOI：
10.1016/0002-9378(75)90722-x
发表时间：
1975-01-01
影响因子：
9.8
作者：
KING, BF;MENTON, DN
通讯作者：
MENTON, DN
DOI：
10.1007/bf00304738
发表时间：
1988-01-01
期刊：
ANATOMY AND EMBRYOLOGY
影响因子：
--
作者：
LEISER, R;DANTZER, V
通讯作者：
DANTZER, V
DOI：
10.1186/1477-7827-2-46
发表时间：
2004-07-05
期刊：
Reproductive biology and endocrinology : RB&E
影响因子：
--
作者：
Carter, Anthony M;Enders, Allen C
通讯作者：
Enders, Allen C
影响因子：
3.8
作者：
Enders, AC;Carter, AM
通讯作者：
Carter, AM