Genetic influences on learning disabilities: an update.
Genetic influences on learning disabilities: an update.
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遗传对学习障碍的影响：更新。
DOI：
10.1037//0022-006x.56.6.817
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发表时间：
1988
影响因子：
5.9
通讯作者：
Smith,SD
中科院分区：
文献类型：
--
作者：
Pennington,BF;Smith,SD
这篇选择性综述考察了遗传对学习障碍的影响。我们讨论了分子遗传学的最新进展，这些进展使连锁分析成为研究行为表型遗传学的更强大的工具。我们还检查了已知的两种家族性疾病，发育性阅读障碍和多发性抽动症(TS)的遗传影响。虽然TS不是一种LD，但有人声称它与LDS以及其他相关的行为表型有关。我们简要地考虑了一种相反的策略来检查遗传对LDS的影响，即从已知的基因改变开始，并检查它是否导致特定的LD表型。我们还讨论了必须满足的标准，然后我们才能得出结论，要么表型是受遗传影响的，要么是已知的基因改变导致特定的和一致的认知表型。当满足这些标准时，研究遗传对LDS的影响可以成为告诉我们认知发展的神经生物学的有力方法。
The present selective review examines genetic influences on learning disabilities (LDs). We discuss recent advances in molecular genetics that have made linkage analysis a more powerful tool for studying the genetics of behavioral phenotypes. We also examine what is known about genetic influences in two familial disorders, developmental dyslexia and Tourette syndrome (TS). Although TS is not a LD, there are claims that it is associated with LDs as well as with other related behavioral phenotypes. We briefly consider an opposite strategy for examining genetic influences on LDs, that is, by beginning with a known genetic alteration and examining whether it leads to a specific LD phenotype. We also discuss criteria that must be satisfied before we can conclude either that a phenotype is genetically influenced or that a known genetic alteration leads to a specific and consistent cognitive phenotype. When these criteria are met, the study of genetic influences on LDs can be a powerful method for informing us about the neurobiology of cognitive development.
吉尔·德拉图雷特综合症
影响因子：
3.4
作者：
A. Friedhoff
通讯作者：
A. Friedhoff
临床神经心理学杂志
DOI：
--
发表时间：
1981
期刊：
影响因子：
--
作者：
L. Costa;B. Rourke;K. Adams;D. Bakker;A. Benton;R. Broughton;G. G. Brown;M. Bryden
通讯作者：
M. Bryden
影响因子：
7.6
作者：
S. G. Vandenberg;S. Singer;D. Pauls
通讯作者：
D. Pauls