Transfer of learning but not memory after unilateral cerebellar lesion in rabbits.

Transfer of learning but not memory after unilateral cerebellar lesion in rabbits.
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兔子单侧小脑损伤后学习能力转移但记忆不转移。

DOI:
10.1037//0735-7044.108.2.284
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发表时间:
1994
影响因子:
1.9
通讯作者:
Clark,RE
Clark,RE
中科院分区:
医学4区
文献类型:
--
作者:
Lavond,DG;Kanzawa,SA;Ivkovich,D;Clark,RE

文献摘要

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兔单侧小脑损伤完全和永久地消除了以前的学习和防止新的学习同侧病变。然而,当在对侧继续训练时,由于需要很少的试验来学习,因此有大量的节省。这一观察结果可能意味着记忆在损伤后仍然存在。兔经典条件眼睑反应,然后同侧小脑间位核被损毁。然后在对侧训练兔子。如果不首先尝试在受损侧进行训练,对侧不会有任何节省。作者得出结论,损伤后记忆的存活可能并不能解释快速转移,而是在以前的研究中试图在损伤侧训练的行为首先在对侧诱导了新的记忆。
Unilateral lesion of the cerebellum in rabbits completely and permanently abolishes previous learning and prevents new learning ipsilateral to the lesion. However, when training continues on the contralateral side, there is substantial savings in that it takes few trials to learn. This observation may imply that the memory survives the lesion. Rabbits were classically conditioned for an eyelid response and then the ipsilateral interpositus nucleus of the cerebellum was lesioned. Then the rabbits were trained on the contralateral side. There is no savings on the contralateral side without first trying to train on the lesioned side. The authors conclude that the survival of a memory after the lesion probably does not account for the rapid transfer, but rather that the act of trying to train on the lesioned side in previous studies first induces a new memory on the contralateral side.
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